An altitude simulation of a trek from ground level to the altitude of Namche Bazaar, Nepal (11,500 ft) was completed at the Duke Center for Hyperbaric Medicine & Environmental Physiology. Six volunteers participated in this study primarily to examine differences between experienced climbers and altitude naïve subjects with regard to epigenetic changes. Standing in the photo are James Logan, MD, Aaron Walker, Richard Moon, MD, Mike Natoli, Sonny Boso, Stefanie Martina, 6 volunteer subjects and Logan Barber, RN. Kneeling: Kay Mitchell, RN from Xtreme Everest2, UK and Nelson Diamond. Not shown: Claude Piantadosi, MD, Jake Freiberger, MD, Bruce Derrick, MD, Eric Schinazi, Tommy Edwards, Robert Brown, Mark Wright, Philip Ramirez, Kevin Kraft, RN, Josh Smith.