Noa Segall, PhD, Assistant Professor of Anesthesiology and Human Factors Engineer in the Human Simulation and Patient Safety Center, received a 5-year, $1,246,724, AHRQ Health Services Research Project (R01) entitled “Effect of Monitoring System Design on Response Time to Cardiac Arrhythmias.” To increase the potential for timely detection and treatment of cardiac events, hospitals have implemented a number of different cardio-respiratory monitoring systems for patients who meet at-risk criteria. However, decisions regarding how to structure and staff monitoring systems have historically been made with very little supporting evidence. We propose to use simulation to identify and test determinants of effective cardiac monitoring. The knowledge to be gained will inform the development of evidence-based monitoring standards. The application of such standards is expected to improve survival after in-hospital cardiac arrest.