Congratulations to Nathan Waldron, MD, CA-2 Resident, along with his mentor Joseph Mathew, MD, MBA, MHSc, Jerry Reves, MD, Professor of Cardiac Anesthesiology and Chairman, Department of Anesthesiology, on their one-year, $75,000 Research Fellowship Grant from the Foundation for Anesthesia Education and Research (FAER) for their proposal titled, “Temporary autonomic blockade to prevent atrial fibrillation after cardiac surgery.”
Postoperative atrial fibrillation (POAF) is the most common complication after cardiac surgery, and is associated with increased morbidity, mortality, and hospital length of stay (LOS), resulting in greater healthcare costs. Despite intensive study, the incidence of POAF is essentially unchanged (»40%) over the last twenty years, suggesting that new therapeutic approaches are urgently needed. While the autonomic nervous system is implicated in the pathogenesis of atrial fibrillation, there are few strategies to prevent POAF targeted at autonomic modulation. In this study, the investigators intend to determine whether autonomic modulation via botulinum toxin injected in the epicardial fat pads is efficacious and safe for decreasing POAF after cardiac surgery.