Duke Anesthesiology’s Ambulatory Anesthesia Division and the Brain Imaging and Analysis Center collaborate on research that provides insight into brain networks during peripheral nerve blocks (PNB) and PNB recovery.
The article is published in the August 2016 issue of the journal, Anesthesiology, titled “Changes in Brain Resting-State Functional Connectivity Associated with Peripheral Nerve Blockade: A Pilot Study.” Authors of this article include Dr. Steve Melton (first author), Dr. Karen Nielsen and Dr. Stephen Klein (chief of the Ambulatory Anesthesia Division).
The purpose of this study was to test the hypothesis that temporary functional deafferentation through PNB will influence changes in resting-state functional connectivity plasticity in central sensorimotor functional brain networks in healthy human participants. This study provides evidence to suggest that PNB is an attractive intervention to modulate neuroplasticity for future research and/or possible clinical application.
View the full article at http://anesthesiology.pubs.asahq.org/article.aspx?articleid=2528139.