2016 Research Grant Awards

The following departmental faculty were awarded competitive and non-competitive research grants during calendar year 2016.

Ru-Rong Ji, PhD

Ru-Rong Ji, PhD
Hemichannels, Astrocytic Release, and Neuropathic Pain
Award Date: 9/27/2016
Funding Agency: National Institute of Dental and Craniofacial Research (NIH)
Grant Amount: $100,000

Andrea Nackley, PhD

Andrea G. Nackley, PhD
Proteins, MicroRNAs and Genes Associated with TMD and Overlapping Conditions
Award Date: 9/23/2016
Funding Agency: National Institute of Dental and Craniofacial Research (NIH)
Grant Amount: $586,001

Miles Berger, MD, PhD

Miles Berger, MD, PhD
The Role of MCP1 and Monocyte Activation Within the Central Nervous System in Human Postoperative Cognitive Dysfunction and Delirium
Award Date: 9/20/2016
Funding Agency: Society for Neuroscience in Anesthesiology and Critical Care
Grant Amount: $5,000

Stuart Grant, MB

Stuart A. Grant, MB, ChB
Human Fresh Tissue Lab
Award Date: 9/13/2016
Funding Agency: Halyard Health, Inc.
Grant Amount: $20,610

Wei Yang, PhD

Wei Yang, PhD
The Unfolded Protein Response and Neuroprotection in Stroke
Co-PIs:  Dr. Wulf Paschen, Dr. Huaxin Sheng
Award Date: 9/7/2016
Funding Agency: National Institute of Neurological Disorders and Stroke (NINDS)
Grant Amount: $1,739,065

Lance A. Roy, MD

Lance A. Roy, MD
Fellowship Grant – Anesthesiology Pain Fellowship
Award Date: 9/7/2016
Funding Agency: Boston Scientific Corporation
Grant Amount: $15,000

Lance A. Roy, MD

Lance A. Roy, MD
Medtronic Fellowship Grant 2016-2017
Award Date: 8/23/2016
Funding Agency: Medtronic, Inc.
Grant Amount: $20,000

Madhav Swaminathan, MD, FASE, FAHA

Madhav Swaminathan, MD, FASE, FAHA
Angion AKI
Award Date: 8/18/2016
Funding Agency: Angion Biomedica Corp.
Grant Amount: $217,803

Niccolo Terrando, PhD - 2016 DIG Winner

Niccolo Terrando, PhD
Role of TLR4 in Surgery-Induced Cognitive Decline
Award Date: 8/10/2016
Funding Agency: Takeda Pharmaceutical Company Limited
Grant Amount: $108,888

Jeffrey M. Taekman, MD

Jeffrey M. Taekman, MD
Exploring the Impact of Perioperative Galacto-Oligosaccharides (GOS) on Stress, Anxiety and Cognition
Award Date: 8/5/2016
Funding Agency: Clasado/Host Therabiomics
Grant Amount: $69,885

David S. Warner, MD

David S. Warner, MD
Integrated Training in Anesthesiology Research (T-32)
Award Date: 7/21/2016
Funding Agency: National Institutes of Health
Grant Amount: $1,481,070

Joseph Mathew, MD

Joseph P. Mathew, MD, MHSc, MBA
Cognitive Effects of Body Temperature During Hypothermic Circulatory Arrest
Co-PI: G. Charles Hughes, MD
Award Date: 7/13/2016
Funding Agency: National Heart, Lung, and Blood Institute/NIH
Grant Amount: $3,500,000

Noa Segall, PhD

Noa Segall, PhD
Identifying Best Practices in In-Hospital Monitoring
Award Date: 7/8/2016
Funding Agency: Saint Alphonsus Regional Medical Center
Grant Amount: $15,611

Ashraf S. Habib, MBBCh, MSc, MHSc, FRCA

Ashraf S. Habib, MBBCh, MSc, MHSc, FRCA
Impact of Local Anesthetic Wound Infiltration on Postoperative Pain Following Cesarean Delivery
Award Date: 7/7/2016
Funding Agency: Halyard Health, Inc.
Grant Amount: $28,841

Niccolo Terrando, PhD - 2016 DIG Winner

Niccolo Terrando, PhD
Bioelectronic Medicine and Cholinergic Regulation of Postoperative Cognitive Dysfunction
Award Date: 7/1/2016
Funding Agency: Duke Institute for Brain Sciences (DIBS)
Grant Amount: $75,000

Mihai V. Podgoreanu, MD

Mihai Podgoreanu, MD, FASE
Sequencing Technology for Rapid Detection of Fastidious and Resistant Infectious Agents in the Critically Ill
Co-PI: Quintin J. Quinones, MD, PhD
Award Date: 7/1/2016
Funding Agency: Duke University Medical Center
Grant Amount: $10,000

Scott Runyon, MD

Scott L. Runyon, MD
Duke Pain Management
Award Date: 6/30/2016
Funding Agency: St. Jude Medical Inc.
Grant Amount: $25,000

Zhiquan Zhang, PhD

Zhiquan Zhang, PhD
Proteomic Identification of Novel Sirtuin-3 Regulated Pathways in the Treatment of Acute Myocardial Ischemia-Reperfusion
Award Date: 6/27/2016
Funding Agency: Duke University Medical Center
Grant Amount: $10,000

Sven-Eric Jordt, PhD

Sven-Eric Jordt, PhD
Mechanisms of Itch in Poison Ivy-Induced Allergic Contact Dermatitis
Award Date: 6/24/2016
Funding Agency: National Institute of Arthritis and Musculoskeletal and Skin Diseases (R21)
Grant Amount: $384,780

Ian J. Welsby, MB BS

Ian J. Welsby, MB BS
CSL Cryoprecipitate Characterization
Award Date: 6/23/2016
Funding Agency: CSL Behring LLC
Grant Amount: $171,697

Michael L. James, MD, FAHA, FNCS

Michael “Luke” James, MD, FAHA, FNCS
Cephalogics DOT 3.0 in Cerebral Vasospasm
Award Date: 6/21/2016
Funding Agency: Cephalogics, LLC
Grant Amount: $284,479

Wulf Paschen, PhD

Wulf Paschen, PhD
Effect of Aging on Brain Ischemia/Stroke Outcome; Pathways, Mechanisms, and Rescue
Award Date: 6/15/2016
Funding Agency: National Institutes of Health
Grant Amount: $1,043,435

Joseph Mathew, MD

Joseph P. Mathew, MD, MHSc, MBA
Temporary Autonomic Blockade to Prevent Atrial Fibrillation After Cardiac Surgery
Fellow: Nathan Waldron, MD
Award Date:
 6/6/2016
Funding Agency: American Heart Association
Grant Amount: $154,000

Wei Yang, PhD

Wei Yang, PhD
ER Stress Response in Recovery of Brain Function After Cardiac Arrest
Co-PIs:  Dr. Wulf Paschen, Dr. Huaxin Sheng
Award Date: 6/6/2016
Award Name: MAA Winter 2016 Grant-in-Aid
Funding Agency: American Heart Association
Grant Amount: $154,000

Ian J. Welsby, MB BS

Ian J. Welsby, MB BS
Factor Concentrate Mayo Study
Award Date: 6/3/2016
Funding Agency: Mayo Clinic
Grant Amount: $59,432

Madan M. Kwatra, PhD

Madan M. Kwatra, PhD
Targeting GBMs with Activated EGFR with Third-Generation, Brain-Penetrating AZD9291
Award Date: 6/1/2016
Funding Agency: Musella Foundation For Brain Tumor Research & Information, Inc
Grant Amount: $8,000

Ankeet D. Udani, MD, MSEd

Ankeet Udani, MD, MSEd
A Comparison of Two Learning Theories on Emergency Manual Use: Classroom-Based Experiential Learning Versus Electronic-Based Self-Directed Learning
Award Date: 4/19/2016
Funding Agency: Anesthesia Patient Safety Foundation
Grant Amount: $147,001

Niccolo Terrando, PhD - 2016 DIG Winner

Niccolo Terrando, PhD
Neuroprotective Effects of URMC-099 in Postoperative Cognitive Dysfunction
Award Date: 4/19/2016
Funding Agency: University of Rochester Medical Center
Grant Amount: $3,000

Kelly Machovec, MD

Kelly A. Machovec, MD, MPH
Open-Label Evaluation of the Population Pharmacokinetic Profile, Safety, Tolerability, and Efficacy of Tapentadol Oral Solution For the Treatment of Post-Surgical Pain in Children Aged from Birth to Less Than 2 Years
Award Date: 4/11/2016
Funding Agency: Grunenthal GmbH
Grant Amount: $50,063

William Maixner, DDS, PhD

William Maixner, DDS, PhD
Genetic and Psychosocial Influences on Transition to Chronic TMD and Related Pain (OPPERA-2)
Award Date: 4/8/2016
Funding Agency: University of North Carolina – Chapel Hill/NIH
Grant Amount: $134,043

Jeffrey C. Gadsden, MD

Jeffrey Gadsden, MD
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block with EXPAREL for Postsurgical Analgesia in Subjects Undergoing Total Shoulder Arthroplasty or Rotator Cuff Repair
Award Date: 4/5/2016
Funding Agency: Pacira Pharmaceuticals
Grant Amount: $188,912

Jeffrey C. Gadsden, MD

Jeffrey Gadsden, MD
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy, Safety, and Pharmacokinetics of Femoral Nerve Block with EXPAREL for Postsurgical Analgesia in Subjects Undergoing Total Knee Arthroplasty
Award Date: 3/31/2016
Funding Agency: Pacira Pharmaceuticals
Grant Amount: $184,034

Bret Stolp, MD

Bryant W. Stolp, MD, PhD
CareFusion Anesthesia
Award Date: 3/10/2016
Funding Agency: CareFusion Corporation
Grant Amount: $8,280

Nathaniel Greene, MD

Nathaniel H. Green, MD
A Phase IIA, Open label, Safety and Pharmacokinetic Study of Tivorbex® Capsules in Pediatric Subjects 6 to <17 (exclusive) Years of Age with Mild to Moderate Acute Postoperative Pain
Following Elective Surgery

Award Date: 2/24/2016
Funding Agency: Iroko Pharmaceuticals, LLC
Grant Amount: $72,664

Ashraf S. Habib, MBBCh, MSc, MHSc, FRCA

Ashraf S. Habib, MBBCh, MSc, MHSc, FRCA
Randomized, Double-Blind, Placebo-Controlled Study of APD421 (Amisulpride for IV Injection) as Treatment of Established Post-Operative Nausea and Vomiting, in Patients who Have had no Prior Prophylaxis
Award Date: 2/22/2016
Funding Agency: Acacia Pharma
Grant Amount: $293,163

Noa Segall, PhD

Noa Segall, PhD
Right Place, Right Time: Information Design to Support Decisions in Acute Care
Award Date: 2/8/2016
Funding Agency: Saint Alphonsus Regional Medical Center/NIH
Grant Amount: $100,800

Madhav Swaminathan, MD, FASE, FAHA

Madhav Swaminathan, MD, FASE, FAHA
A Randomized, Double-Blind, Placebo Controlled, Phase 2 Study to Evaluate the Efficacy and Safety of QPI-1002 for the Prevention of Acute Kidney Injury in Subjects at High Risk for AKI following Cardiac Surgery
Award Date: 1/5/2016
Funding Agency: Quark Pharmaceuticals, Inc
Grant Amount: $229,715