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Department:
Anesthesiology
Division:
Anesthesiology
Mailing Address:
DUMC 3094
Durham, NC 27710
Appointment Telephone:
919-681-2150
Office Telephone:
919-681-2150
Fax:
919-681-4698
Training:
MD, Hahnemann (Drexel University College of Medicine, Pennsylvania), 1977
Fellowship:
Critical Care Medicine, Maryland Institute for Emergency Medical Services, 1980
Residency:
Internal Medicine, Robert Packer Hospital/Guthrie Clinic (Pennsylvania), 1977-1980
Clinical Interests:
Neuro-critical care, neuroanesthesiology
Research Interests:
My long term career interests center around anesthesia and critical care for patients with life-threatening neurological illnesses. I am particularly interested in respiratory dysfunction as the result of neurocritical illness. Recently I have been involved with projects to explore the pathophysiology of cerebral vasospasm following subarachnoid hemorrhage in vivo and in vitro models, the role of magnesium in cerebral vasospasm, and technical aspects of neuroanesthesia related to awake craniotomy and endovascular cerebrovascular surgery.
Publications:
Borel CO, McKee A, Parra A, Haglund MM, Solan A, Prabhakar V, Sheng H, Warner DS, Niklason L. Possible role for vascular cell proliferation in cerebral vasospasm after subarachnoid hemorrhage. Stroke. 2003 Feb;34(2):427-33.
Fabling JM, Gan TJ, El-Moalem HE, Warner DS, Borel CO. A randomized, double-blind comparison of ondansetron versus placebo for prevention of nausea and vomiting after infratentorial craniotomy. J Neurosurg Anesthesiol. 2002 Apr;14(2):102-7.
Brewer RP, Parra A, Lynch J, Chilukuri V, Borel CO. Cerebral blood flow velocity response to magnesium sulfate in patients after subarachnoid hemorrhage. J Neurosurg Anesthesiol. 2001 Jul;13(3):202-6.
Fabling JM, Gan TJ, El-Moalem HE, Warner DS, Borel CO. A randomized, double-blinded comparison of ondansetron, droperidol, and placebo for prevention of postoperative nausea and vomiting after supratentorial craniotomy. Anesth Analg. 2000 Aug;91(2):358-61.
Bushnell CD, Phillips-Bute BG, Laskowitz DT, Lynch JR, Chilukuri V, Borel CO. Survival and outcome after endotracheal intubation for acute stroke. Neurology. 1999 Apr 22;52(7):1374-81.
Borel CO, Guy J, Barcik U, Natoli MJ, Vann RD. Effect of hypobaria on ventilatory and CO2 responses to short-term hypoxic exposure in cats. Respir Physiol. 1998 Jan;111(1):45-53.
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