Philanthropy

Congratulations to our three, 2014 DIG winners!

After careful consideration, the DIG Application Review Committee, comprised of: Dr. Manuel Fontes, Dr. Tong-Joo Gan , Dr. Ru-Rong Ji, Dr. Joseph Mathew, Dr. Richard Moon, Dr. Mark Newman, Dr. Mihai Podgoreanu, Dr. Andrew Shaw, Dr. Mark Stafford-Smith, and Dr. David Warner, selected three research studies to receive the grant. 

Read more

Spring 2013 DIG Report: Miklos Kertai, MD, PhD

Pharmacogenomics of β-blockers: Implication for Postoperative Atrial Fibrillation Miklos Kertai, MD, PhD The purpose of our study is to identify genetic variations in human genes that are responsible for modulating the efficacy of beta-blockers for the prevention of postoperative atrial fibrillation. For the purposes of the present study, we are using isolated DNA and human atrial tissue from patients who...

Spring 2013 DIG Report: Steve Melton, MD

Neurointerventional Regional Anesthesia to Improve Hand Rehabilitation in Stroke Steve Melton, MD This collaborative research project between investigators from anesthesiology, physical therapy, and neurology is proceeding as planned. Initial groundwork, preparation, and coordination have occurred to facilitate successful recruitment, enrollment and implementation of the study design and data collection. Additionally, the group is in the process of preparing multiple manuscripts related to our...

Spring 2013 DIG Report: Michael W. Manning, MD, PhD

Cardiopulmonary Bypass Induced Inflammatory Changes in the Atrial Wall: The Novel Role for Cardiac Chymase produced Angiotensin II in the Development of Atrial Fibrillation Michael Manning, MD, PhD Over the last four months, I have been working to establish many of the tools that we will need to conduct these new and exciting experiments. First, we now have working protocols in place that...

Spring 2013 DIG Report: Karthik Raghunathan, MD, MPH

Comparative effectiveness in Perioperative and Critical Care Medicine: Crystalloid Fluid Therapy Karthik Raghunathan, MD, MPH Balanced salt solutions are often used for the treatment of dehydration among patients undergoing surgical procedures, while intravenous saline solutions are the most commonly used fluid among patients with serious infections. Our preliminary analysis of over 50,000 patients with serious infections admitted to intensive care units in...

Winter 2012 DIG Report: Mihai V. Podgoreanu, MD

Elucidating Adaptive Mechanisms of Perioperative Cardioprotection Following Ischemia-reperfusion in Hibernating Arctic Ground Squirrels Mihai V. Podgoreanu, MD The overall goal of this study was to understand how hibernating animals have developed natural defense mechanisms to withstand extremes of environment, and to ultimately apply this knowledge for organ protection in humans undergoing...