Clasado/Host Therabiomics has awarded Duke Anesthesiology’s Dr. Jeffrey Taekman $69,885 in funding for a clinical trial titled, “Exploring the Impact of Perioperative Galacto-Oligosaccharides (GOS) on Stress, Anxiety and Cognition.”
Studies link the gut microbiota to the function of the central nervous system, both in behavior and cognition. Prebiotics stimulate growth of beneficial bacteria in the gut. The overall objective of this proposal is to explore, in the perioperative period, the association between the administration of the prebiotic GOS and pain, anxiety and cognitive function. His central hypothesis is subjects who consume GOS in the perioperative period will demonstrate lower levels of salivary cortisol before, during, and after their operative procedures. In addition, he expects subjects who consume GOS to have lower perceived levels of anxiety during the perioperative period. Finally, he hypothesizes that subjects who consume perioperative GOS will perform better on tests of cognition in the postoperative period.
Dr. Taekman is a professor of anesthesiology, the assistant dean for educational technology, and the director of the Duke Human Simulation and Patient Safety Center. He is currently a fellow in the University of Arizona’s Center for Integrative Medicine where he is pursuing his interests in the medicinal use of food as well as mind-body medicine.