Dr. Browndyke’s winning abstract is titled, “Resting-state Brain Functional Connectivity Changes Associated with Cognitive Outcomes Following Cardiac Surgery.” This is the eighth year the popular award was presented at the American Society of Anesthesiologists Conference.
2015 ASA Abstract Summary (presented by Jeff Browndyke, PhD, Department of Psychiatry and Behavioral Sciences):
Postoperative cognitive dysfunction (POCD), a common post-acute cognitive syndrome observed in patients after major surgery, is associated with increased late-life dementia and mortality risks. Debate has raged about the level of cognitive change necessary for POCD and whether the condition may be peripheral to other factors, such as negative mood, but little has been described about neuropathological mechanisms underlying the syndrome in postoperative patients with a spectrum of cognitive outcomes. In this functional neuroimaging and cognition study, we provide the first evidence that the magnitude of cognitive change seen in patients at 6-weeks after cardiac surgery is positively associated with regional changes in functional brain organization from baseline.