Duke Pain Journal Club - "TIAM1-mediated synaptic plasticity underlies comorbid depression–like and ketamine antidepressant–like actions in chronic pain"

Ru Q, Lu Y, Saifullah AB, Blanco FA, Yao C, Cata JP, Li DP, Tolias KF, Li L. TIAM1-mediated synaptic plasticity underlies comorbid depression-like and ketamine antidepressant-like actions in chronic pain. J Clin Invest. 2022 Dec 15;132(24):e158545. doi: 10.1172/JCI158545. PMID: 36519542; PMCID: PMC9753999. | Presenter: Mona Hashemaghaie, MD | Laboratory Affiliation: Treggiari/Nackley Laboratories