Niccolò
Terrando
Professor of Anesthesiology
Professor in Integrative Immunobiology
Professor in Cell Biology
Faculty Network Member of the Duke Institute for Brain Sciences
Addresses
- 3 Genome Ct, Msrbiii Room 6144, Durham, NC 27710
Education
- Ph.D. 2007 - Imperial College London (United Kingdom)
Grants
- IL-6 Trans-signaling increases vulnerability to Postoperative Cognitive Decline in Aging and Alzheimers Disease awarded by University of California - San Francisco 2024 - 2029
- The role of cerebrospinal fluid complement activation in delirium and post-intensive care unit long-term cognitive impairment awarded by National Institutes of Health 2024 - 2029
- Translational Center for Barrier Microphysiological Systems awarded by University of Rochester 2024 - 2028
- Microglia-Amyloid interactions in delirium superimposed on dementia awarded by National Institute on Aging 2017 - 2027
- The impacts of postoperative delirium on AD progression awarded by Alzheimer's Association 2024 - 2027
- Unveiling the Neurovascular Responses to Amyloid-Beta Antibodies: A Neurovascular Unit-on-a-Chip Approach for Personalized Passive Immunotherapy awarded by Alzheimer's Association 2024 - 2026
- Cell and Molecular Biology Training Program awarded by National Institutes of Health 2021 - 2026
- Integrated Training in Anesthesiology Research awarded by National Institutes of Health 1996 - 2026
- Protective role of Clec7a/dectin-1 in CNS autoimmunity awarded by National Institute of Neurological Disorders and Stroke 2020 - 2025
- Development of Adrb3 Antagonists for the Treatment of Pain awarded by National Institutes of Health 2023 - 2025
Publications
- Payne, Thomas, Jennifer Taylor, David Kunkel, Katherine Konieczka, Frankie Ingram, Kaj Blennow, Henrik Zetterberg, et al. “Association of preoperative to postoperative change in cerebrospinal fluid fibrinogen with postoperative delirium.” BJA Open 12 (December 2024): 100349. https://doi.org/10.1016/j.bjao.2024.100349.
- Wu, Pau Yen, Ana Isabel Caceres, Jiegen Chen, Jamie Sokoloff, Mingjian Huang, Gurpreet Singh Baht, Andrea G. Nackley, Sven-Eric Jordt, and Niccolò Terrando. “Vagus nerve stimulation rescues persistent pain following orthopedic surgery in adult mice.” In Pain, 165:e80–92, 2024. https://doi.org/10.1097/j.pain.0000000000003181.
- Li, Herman, Niccolò Terrando, and Harris A. Gelbard. “Infectious Diseases.” Adv Neurobiol 37 (2024): 423–44. https://doi.org/10.1007/978-3-031-55529-9_24.
- Devinney, Michael J., Megan K. Wong, Mary Cooter Wright, Edward R. Marcantonio, Niccolò Terrando, Jeffrey N. Browndyke, Heather E. Whitson, et al. “Role of Blood-Brain Barrier Dysfunction in Delirium following Non-cardiac Surgery in Older Adults.” Ann Neurol 94, no. 6 (December 2023): 1024–35. https://doi.org/10.1002/ana.26771.
- Li, Herman, Linh Le, Mariah Marrero, Jennifer David-Bercholz, Ana I. Caceres, Claire Lim, Wesley Chiang, Ania K. Majewska, Niccolò Terrando, and Harris A. Gelbard. “Neutrophilia with damage to the blood-brain barrier and neurovascular unit following acute lung injury.,” October 17, 2023. https://doi.org/10.1101/2023.10.16.562508.
- Chiang, Wesley, Angela Stout, Francine Yanchik-Slade, Herman Li, Niccolò Terrando, Bradley L. Nilsson, Harris A. Gelbard, and Todd D. Krauss. “Quantum Dot Biomimetic for SARS-CoV-2 to Interrogate Blood-Brain Barrier Damage Relevant to NeuroCOVID Brain Inflammation.” ACS Appl Nano Mater 6, no. 16 (August 25, 2023): 15094–107. https://doi.org/10.1021/acsanm.3c02719.
- Walker, Keenan A., Lydia M. Le Page, Niccolò Terrando, Michael R. Duggan, Michael T. Heneka, and Brianne M. Bettcher. “The role of peripheral inflammatory insults in Alzheimer's disease: a review and research roadmap.” Mol Neurodegener 18, no. 1 (June 5, 2023): 37. https://doi.org/10.1186/s13024-023-00627-2.
- Lascola, Christopher D., Sarah F. Cotter, Rebecca Y. Klinger, Tiffany Bisanar, Mary Cooter Wright, Miles Berger, Gavin Martin, et al. “Blood-brain barrier permeability and cognitive dysfunction after surgery - A pilot study.” J Clin Anesth 86 (June 2023): 111059. https://doi.org/10.1016/j.jclinane.2023.111059.
- Wu, Pau Yen, Ana Isabel Caceres, Jiegen Chen, Jamie Sokoloff, Mingjian Huang, Gurpreet Singh Baht, Andrea G. Nackley, Sven-Eric Jordt, and Niccolò Terrando. “Vagus nerve stimulation rescues persistent pain following orthopedic surgery in adult mice.,” May 17, 2023. https://doi.org/10.1101/2023.05.16.540949.
- Devinney, Michael J., Megan K. Wong, Mary Cooter Wright, Edward R. Marcantonio, Niccolò Terrando, Jeffrey N. Browndyke, Heather E. Whitson, et al. “A Role for Blood-brain Barrier Dysfunction in Delirium following Non-Cardiac Surgery in Older adults.” MedRxiv, May 10, 2023. https://doi.org/10.1101/2023.04.07.23288303.
Past Appointments
- Associate Professor in Cell Biology
- Associate Professor in Integrative Immunobiology
- Associate Professor of Anesthesiology
- Associate Professor in Immunology
- Associate Professor in Anesthesiology
- Assistant Research Professor in Cell Biology
- Assistant Professor in Anesthesiology
Newsfeeds
- In Pre-Clinical Studies, Fish Oil Helps Prevent Post-Operative Delirium
- Nerve Stimulation in Mice Suggests New Way to Reduce Delirium After Surgery
- Supplemental Grant Aids Search for Answers to Post-Anesthesia Memory Problems
Courses
- NEUROSCI 495: Research Independent Study 3
- NEUROSCI 494: Research Independent Study 2
- NEUROSCI 493: Research Independent Study 1
Professor of Anesthesiology
3 Genome Ct, Msrbiii Room 6144, Durham, NC 27710