Selected Publications

  1. Acker L, Wong MK, Wright MC, Reese M, Giattino CM, Roberts KC, Au S, Colon-Emeric C, Lipsitz LA, Devinney MJ, Browndyke J, Eleswarpu S, Moretti E, Whitson HE, Berger M, Woldorff MG; INTUIT and PRIME study groups. Preoperative electroencephalographic alpha-power changes with eyes opening are associated with postoperative attention impairment and inattention-related delirium severity. Br J Anaesth. 2024 Jan;132(1):154-163. doi: 10.1016/j.bja.2023.10.037. Epub 2023 Dec 12. PMID: 38087743; PMCID: PMC10797508.
  2. Youssef A, Rehman AU, Elebasy M, Roper J, Sheikh SZ, Karhausen J, Yang W, Ulloa L. Vagal stimulation ameliorates murine colitis by regulating SUMOylation. Sci Transl Med. 2024 Nov 20;16(774): eadl2184. doi: 10.1126/scitranslmed. adl2184. Epub 2024 Nov 20. PMID: 39565873.
  3. Youssef A, Mohammed BK, Prasad A, Del Aguila A, Bassi G, Yang W, Ulloa L. Splenic SUMO1 controls systemic inflammation in experimental sepsis. Front Immunol. 2023 Jul 13; 14:1200939. doi: 10.3389/fimmu.2023.1200939. PMID: 37520526; PMCID: PMC10374847.
  4. Sheng H, Spasojevic I, Tse HM, Jung JY, Hong J, Zhang Z, Piganelli JD, Batinic-Haberle I, Warner DS. Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage. J Pharmacol Exp Ther. 2011 Sep;338(3):906-16. doi: 10.1124/jpet.110.176701. Epub 2011 Jun 7. PMID: 21652782; PMCID: PMC3164343.
  5. Chen Y, Lu X, Whitney RL, Li Y, Robson MJ, Blakely RD, Chi JT, Crowley SD, Privratsky JR. Novel anti-inflammatory effects of the IL-1 receptor in kidney myeloid cells following ischemic AKI. Front Mol Biosci. 2024 Apr 17; 11:1366259. doi: 10.3389/fmolb.2024.1366259. PMID: 38693918; PMCID: PMC11061482.
  6. Berger M, Ryu D, Reese M, McGuigan S, Evered LA, Price CC, Scott DA, Westover MB, Eckenhoff R, Bonanni L, Sweeney A, Babiloni C. A Real-Time Neurophysiologic Stress Test for the Aging Brain: Novel Perioperative and ICU Applications of EEG in Older Surgical Patients. Neurotherapeutics. 2023 Jul;20(4):975-1000. doi: 10.1007/s13311-023-01401-4. Epub 2023 Jul 12. Erratum in: Neurotherapeutics. 2024 Oct;21(6):e00473. doi: 10.1016/j.neurot. 2024.e00473. PMID: 37436580; PMCID: PMC10457272.
  7. VanDusen KW, Eleswarpu S, Moretti EW, Devinney MJ, Crabtree DM, Laskowitz DT, Woldorff MG, Roberts KC, Whittle J, Browndyke JN, Cooter M, Rockhold FW, Anakwenze O, Bolognesi MP, Easley ME, Ferrandino MN, Jiranek WA, Berger M; MARBLE Study Investigators. The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction. J Alzheimers Dis. 2020;75(4):1319-1328. doi: 10.3233/JAD-191185. PMID: 32417770; PMCID: PMC7923142.
  8. Kertai MD, Ji Y, Li YJ, Mathew JP, Daubert JP, Podgoreanu MV; PEGASUS Investigative Team. Interleukin-1β gene variants are associated with QTc interval prolongation following cardiac surgery: a prospective observational study. Can J Anaesth. 2016 Apr;63(4):397-410. doi: 10.1007/s12630-015-0576-8. Epub 2016 Feb 8. PMID: 26858093; PMCID: PMC5048102.
  9. Kertai MD, Li YW, Li YJ, Shah SH, Kraus WE, Fontes ML, Stafford-Smith M, Newman MF, Podgoreanu MV, Mathew JP; Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team. G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers. Circ Cardiovasc Genet. 2014 Oct;7(5):625-633. doi: 10.1161/CIRCGENETICS.113.000451. Epub 2014 Jul 21. PMID: 25049040; PMCID: PMC4270923.
  10. Huffman WJ, Subramaniyan S, Rodriguiz RM, Wetsel WC, Grill WM, Terrando N. Modulation of neuroinflammation and memory dysfunction using percutaneous vagus nerve stimulation in mice. Brain Stimul. 2019 Jan-Feb;12(1):19-29. doi: 10.1016/j.brs.2018.10.005. Epub 2018 Oct 9. PMID: 30337243; PMCID: PMC6301148.
  11. Schrepf A, Maixner W, Fillingim R, Veasley C, Ohrbach R, Smith S, Williams DA. The Chronic Overlapping Pain Condition Screener. J Pain. 2024 Jan;25(1):265-272. doi: 10.1016/j.jpain.2023.08.009. Epub 2023 Aug 24. PMID: 37633574.
  12. Chandra S, Wang Z, Tao X, Chen O, Luo X, Ji RR, Bortsov AV. Computer-aided Discovery of a New Nav1.7 Inhibitor for Treatment of Pain and Itch. Anesthesiology. 2020 Sep;133(3):611-627. doi: 10.1097/ALN.0000000000003427. PMID: 32788559.
  13. Wang Y, Kim SH, Klein ME, Chen J, Gu E, Smith S, Bortsov A, Slade GD, Zhang X, Nackley AG. A mouse model of chronic primary pain that integrates clinically relevant genetic vulnerability, stress, and minor injury. Sci Transl Med. 2024 Apr 10;16(742): eadj0395. doi: 10.1126/scitranslmed. adj0395. Epub 2024 Apr 10. PMID: 38598615.
  14. Zhang X, Hartung JE, Bortsov AV, Kim S, O'Buckley SC, Kozlowski J, Nackley AG. Sustained stimulation of β2- and β3-adrenergic receptors leads to persistent functional pain and neuroinflammation. Brain Behav Immun. 2018 Oct; 73:520-532. doi: 10.1016/j.bbi.2018.06.017. Epub 2018 Jun 20. PMID: 29935309; PMCID: PMC6129429.
  15. Ciszek BP, O'Buckley SC, Nackley AG. Persistent Catechol-O-methyltransferase-dependent Pain Is Initiated by Peripheral β-Adrenergic Receptors. Anesthesiology. 2016 May;124(5):1122-35. doi: 10.1097/ALN.0000000000001070. PMID: 26950706; PMCID: PMC5015695.
  16. Hartung JE, Ciszek BP, Nackley AG. β2- and β3-adrenergic receptors drive COMT-dependent pain by increasing production of nitric oxide and cytokines. Pain. 2014 Jul;155(7):1346-1355. doi: 10.1016/j.pain.2014.04.011. Epub 2014 Apr 13. PMID: 24727346; PMCID: PMC4086872.
  17. Wright NJ, Matsuoka Y, Park H, He W, Webster CG, Furutani K, Fedor JG, McGinnis A, Zhao Y, Chen O, Bang S, Fan P, Spasojevic I, Hong J, Ji RR, Lee SY. Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief. Nat Commun. 2024 Dec 30;15(1):10738. doi: 10.1038/s41467-024-54914-7. PMID: 39737929; PMCID: PMC11685430.
  18. Donnelly CR, Jiang C, Andriessen AS, Wang K, Wang Z, Ding H, Zhao J, Luo X, Lee MS, Lei YL, Maixner W, Ko MC, Ji RR. STING controls nociception via type I interferon signalling in sensory neurons. Nature. 2021 Mar;591(7849):275-280. doi: 10.1038/s41586-020-03151-1. Epub 2021 Jan 13. PMID: 33442058; PMCID: PMC7977781.
  19. Donnelly CR, Chen O, Ji RR. How Do Sensory Neurons Sense Danger Signals? Trends Neurosci. 2020 Oct;43(10):822-838. doi: 10.1016/j.tins.2020.07.008. Epub 2020 Aug 21. PMID: 32839001; PMCID: PMC7530006.
  20. Buchheit T, Huh Y, Breglio A, Bang S, Xu J, Matsuoka Y, Guo R, Bortsov A, Reinecke J, Wehling P, Jun Huang T, Ji RR. Intrathecal administration of conditioned serum from different species resolves Chemotherapy-Induced neuropathic pain in mice via secretory exosomes. Brain Behav Immun. 2023 Jul; 111:298-311. doi: 10.1016/j.bbi.2023.04.013. Epub 2023 May 5. PMID: 37150265; PMCID: PMC10363329.
  21. Yeo M, Chen Y, Jiang C, Chen G, Wang K, Chandra S, Bortsov A, Lioudyno M, Zeng Q, Wang P, Wang Z, Busciglio J, Ji RR, Liedtke W. Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission. Nat Commun. 2021 Oct 27;12(1):6208. doi: 10.1038/s41467-021-26270-3. PMID: 34707084; PMCID: PMC8551327.
  22. Bang S, Donnelly CR, Luo X, Toro-Moreno M, Tao X, Wang Z, Chandra S, Bortsov AV, Derbyshire ER, Ji RR. Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice. Nat Commun. 2021 Mar 17;12(1):1704. doi: 10.1038/s41467-021-21940-8. PMID: 33731716; PMCID: PMC7969930.
  23. Bang S, Xie YK, Zhang ZJ, Wang Z, Xu ZZ, Ji RR. GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain. J Clin Invest. 2018 Aug 1;128(8):3568-3582. doi: 10.1172/JCI99888. Epub 2018 Jul 16. PMID: 30010619; PMCID: PMC6063480.
  24. Nelli A, Wright MC, Gulur P. Green Light-Based Analgesia - Novel Nonpharmacological Approach to Fibromyalgia Pain: A Pilot Study. Pain Physician. 2023 Jul;26(4):403-410. PMID: 37535780.
  25. Kertai MD, Li YW, Li YJ, Shah SH, Kraus WE, Fontes ML, Stafford-Smith M, Newman MF, Podgoreanu MV, Mathew JP; Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team. G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers. Circ Cardiovasc Genet. 2014 Oct;7(5):625-633. doi: 10.1161/CIRCGENETICS.113.000451. Epub 2014 Jul 21. PMID: 25049040; PMCID: PMC4270923.
  26. Kertai MD, Qi W, Li YJ, Lombard FW, Liu Y, Smith MP, Stafford-Smith M, Newman MF, Milano CA, Mathew JP, Podgoreanu MV; Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team. Gene signatures of postoperative atrial fibrillation in atrial tissue after coronary artery bypass grafting surgery in patients receiving β-blockers. J Mol Cell Cardiol. 2016 Mar; 92:109-15. doi: 10.1016/j.yjmcc.2016.02.006. Epub 2016 Feb 6. PMID: 26860460; PMCID: PMC4967350.