To recognize the importance to pharmacology and toxicology of his contributions to basic science, Dr. [Sven-Eric] Jordt has been awarded the 2019 SOT Leading Edge in Basic Science Award.
Dr. Jordt received his PhD from Free University of Berlin in Germany in 1997. He then became a postdoctoral fellow at the Center for Molecular Neurobiology in Hamburg, Germany, and then at the University of California San Francisco Department of Cellular and Molecular Pharmacology. He continues to play a pivotal role in academia through his current positions as an associate professor with the Duke University School of Medicine’s Department of Anesthesiology, with Duke’s University Program of Environmental Health (UPEH), and with the Yale School of Medicine’s Department of Psychiatry.
Dr. Jordt’s work has largely involved TRP channel biology, a cutting-edge area of toxicology within which he is a leader. His extensive investigation of sensory TRP ion channels and their role in responding to physical and chemical signals resulted in the identification of the sensory ion channel TRPA1 as the major receptor for reactive environmental toxicants and inflammatory agents in sensory neurons innervating the airways. Dr. Jordt also focuses on the means by which basic research findings can be translated to applied research in medicine, including asthma research, the discovery of countermeasures against chemical threats, and the health effects of smoking and electronic cigarettes.
Dr. Jordt has been recognized many times within the field of toxicology. For example, he earned an American Asthma Foundation Early Excellence Award because of his work with TRPA1-deficient mice that showed TRPA1’s role in allergic airway inflammation and airway hyperreactivity and bronchoconstriction seen in asthma. He also is a past recipient of the National Institute of Environmental Health Sciences Outstanding New Environmental Scientist Award and the Presidential Early Career Award for Scientists and Engineers.
Dr. Jordt’s expertise has been shared with the scientific and the nonscientific populations. His work has been published in many prestigious scientific journals, and he has authored several book chapters. Additionally, news outlets for the general public, such as CNN, The Wall Street Journal, The Washington Post, and National Public Radio, have interviewed him. He has been an SOT member since 2009.
This award recognizes a scientist who, based on his/her research, has made a recent (within the last five years), seminal scientific contribution/advance to understanding fundamental mechanisms of toxicity. The recipient should be a respected basic scientist whose research findings are likely to have a pervasive impact on the field of toxicology.
Source: Society of Toxicology article (January 7, 2019)