We are pleased to announce that Dr. Ru-Rong Ji, distinguished professor of anesthesiology, has been selected to receive the prestigious 2020 American Society of Anesthesiologists (ASA) Excellence in Research Award. It recognizes individuals for outstanding achievement in research who has or is likely to have an important impact on the practice of anesthesiology. The individual’s work represents a body of original, mature and sustained contribution to the advancement of the science of anesthesiology. This is only one of two awards presented each year by the ASA to recognize the research accomplishments of members of our specialty.
“Several current and previous members of this department have received this award, and I am very proud to be one of them,” says Ji, chief of basic pain research and co-director of the department’s Center for Translational Pain Medicine (CTPM). “I really appreciate the full support I have received from the department over the last eight years.”
Ji’s work has significant translational potential in almost all areas of pain medicine. He currently serves as the director of the Sensory Plasticity and Pain Research Laboratory. Ji’s research focuses on molecular and cellular mechanisms of chronic pain, including but not limited to mediators of inflammation and pain, neuropathic pain, and cancer pain. He is internationally-recognized for his contributions to demonstrating critical roles of MAP kinase signaling pathways, glial cells, and neuroinflammation in the pathogenesis of chronic pain. His work has demonstrated powerful antinociceptive actions of pro-resolution lipid mediators (e.g., resolvins). His lab has shown that resolvins are among the most potent inhibitors for inflammatory pain and TRP channels. He also determined the down-stream GPCR signaling in macrophages and sensory neurons that mediates the potent actions of these lipid mediators. Recently, Ji’s work has focused on unique neuronal signaling of pattern recognition receptors, such as toll-like receptors (TLRs) and their contribution to pain and itch. And, Ji is notably among the first to establish a connection between mediators of cancer and pain processing showing that tumor cells produce PD-L1 to suppress not only the immune system, but also pain perception permitting cancer growth and metastasis. Ji also has established a broad collaboration with CTPM and Duke University School of Medicine faculty members to develop novel pain therapeutics.
“Dr. Ji is an outstanding scientist and colleague. He has a keen wit and is able to move scientific thought to the next level. Furthermore, he has the ability to implement his thoughts and ideas into productive, high-impact research. He clearly merits this award,” says Dr. William Maixner, vice chair for research and co-director of the CTPM.
Ji lectures internationally and reviews papers for numerous international journals. His research has been published in more than 200 peer reviewed manuscripts in high-impact journals, such as Science and Nature. Ji is one of 54 Duke researchers who made the global list of ‘Highly Cited Researchers’ for 2019; a list he also made in 2018. Ji also serves on editorial boards of Anesthesiology, Pain, Journal of Neuroscience, Neuroscience, and Neuroscience Bulletin. He previously served as an associate professor at Brigham and Women’s Hospital, Harvard Medical School, before joining the Duke faculty in 2012. He earned a PhD in neurobiology at Shanghai Institute of Physiology and completed postdoctoral training at Peking (Beijing) University Medical School, Karolinska Institute, and Johns Hopkins University School of Medicine.
Please join us in congratulating Ji on receiving this well-deserved award.