OB Anesthesia Fellowship Alumni | Duke Department of Anesthesiology

OB Anesthesiology Fellow Alumni — Current, future and alumni Duke Obstetric Anesthesia Fellows reunite in Phoenix, Arizona at the SOAP 2019 meeting.

Ilham Eli, MD

2022-2023
Ilham Eli, MD
US Anesthesia Partners
Nashville, Tennessee

Liliane Ernst, MD

2022-2023
Liliane Ernst, MD
Current Duke ACTA Fellow
Duke Anesthesiology
Durham, North Carolina

Publications

Meng ML, Fuller M, Federspiel JJ, Engelhard M, McNeil A, Ernst L, Habib AS, Shah SH, Quist-Nelson J, Raghunathan K, Ohnuma T, Krishnamoorthy V. Maternal Morbidity According to Mode of Delivery Among Pregnant Patients With Pulmonary Hypertension. Anesth Analg. 2023 May 16:10.1213/ANE.0000000000006523. doi: 10.1213/ANE.0000000000006523. Epub ahead of print. PMID: 37192132; PMCID: PMC10651791.

Trung Quoc Pham, MD

2021-2022
Trung Quoc Pham, MD
Associated Anesthesiologist, Inc
Tulsa, Oklahoma

Publications

Mims SC, Tan HS, Sun K, Pham T, Rubright S, Kaplan SJ, Habib AS. Long-term morbidities following unintentional dural puncture in obstetric patients: A systematic review and meta-analysis. J Clin Anesth. 2022 Aug;79:110787. doi: 10.1016/j.jclinane.2022.110787. Epub 2022 Mar 28. PMID: 35358942.

Samatha Rubright, MD

2021-2022
Samatha Rubright, MD
University of Utah
Salt Lake City, Utah

Publications

Olga Diomede, MD

2020-2021
Olga Diomede, MD
Maine Medical Center
Portland, Maine

Publications

Sen Tan H, Diomede O, Habib AS. Postoperative analgesia after cesarean delivery. Int Anesthesiol Clin. 2021 Jul 1;59(3):90-97. doi: 10.1097/AIA.0000000000000321. PMID: 33840755.

Tan HS, Reed SE, Mehdiratta JE, Diomede OI, Landreth R, Gatta LA, Weikel D, Habib AS. Quality of Labor Analgesia with Dural Puncture Epidural versus Standard Epidural Technique in Obese Parturients: A Double-blind Randomized Controlled Study. Anesthesiology. 2022 May 1;136(5):678-687. doi: 10.1097/ALN.0000000000004137. PMID: 35157756.

Sharawi N, Tan HS, Taylor C, Fuller ME, Landreth RA, Diomede OI, Williams M, Martinello C, Mhyre JM, Habib AS. ED 90 of Intrathecal Chloroprocaine With Fentanyl for Prophylactic Cervical Cerclage: A Sequential Allocation Biased-Coin Design. Anesth Analg. 2022 Apr 1;134(4):834-842. doi: 10.1213/ANE.0000000000005927. PMID: 35139044.

Research

Best Clinical Research Paper
1st Place: A Randomized Controlled Trial of Dural Puncture Epidural versus Standard Labor Epidural Technique in Parturients with Obesity

Riley Landreth, DO

2020-2021
Riley Landreth, DO
Assistant Professor of Anesthesiology
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina

Publications

Research

1st Place: SOAP Annual Meeting 2021 Gertie Marx Research Competition
The ED90 of Intrathecal Chloroprocaine for Cervical Cerclage Placement: An Up-Down Sequential Allocation Dose-Response Study

Katherine A. Herbert, MD

2019-2020
Katherine A. Herbert, MD
Assistant Professor
Medical University of South Carolina
Charleston, SC

Publications

Herbert KA, Yurashevich M, Fuller M, Pedro CD, Habib AS. Impact of a multimodal analgesic protocol modification on opioid consumption after cesarean delivery: a retrospective cohort study. J Matern Fetal Neonatal Med. 2021 Jan 3:1-7. PMID: 33393401

Cameron R. Taylor, MD

2018-2019
Cameron R. Taylor, MD
Assistant Professor of Anesthesiology
Duke University School of Medicine
Durham, NC

Publications

Taylor CR, Dominguez JE, Habib AS. (2019) “Obesity and Obstetric Anesthesia: Current Insights.” (2019) Local and Regional Anesthesia. 2019, 12: 111-124. PMID: 31819609.

Presented at SOAP 51st Annual Meeting, May 2019, Phoenix, AZ:

F3I-502: Cameron R Taylor MD; Jennifer Dominguez MD; Ashraf Habib MBBCh A retrospective review of anesthetic management and postoperative analgesic consumption of parturients on buprenorphine maintenance therapy undergoing cesarean delivery.
FCC-314: Cameron R Taylor MD ; Jennifer Dominguez MD; Jennifer Mehdiratta MD; Mary Yurashevich MD; Ashraf Habib MBBCh Tonic-clonic seizure after unrecognized unintentional dural puncture: A case report

Christina (Pedro) Vaquerano, MD

2017-2018
Christina (Pedro) Vaquerano, MD
Chesapeake Anesthesiologists, Inc.
Chesapeake, VA

Publications

Barney EZ, Pedro CD, Gamez BH, Fuller ME, Dominguez JE, Habib AS. (2020) “Wound infusion with ropivacaine and ketorolac for analgesia after cesarean delivery: A randomized, double-blind, placebo-controlled trial.” Obstetrics and Gynecology. 135(2):427-435. PMID: 31923061.

Wood AM, Grotegut CA, Ronald J, Pabon-Ramos W, Pedro C, Knechtle SJ, Wysokinska E, Rubin GD, Brady CW, Gilner JB. “Identification and Management of Abdominal Wall Varices in Pregnancy” Obstetrics and Gynecology. 2018 Oct;132(4):882-887. PMID: 30130349.

Presented at SOAP 50th Annual Meeting, May 2018, Miami, FL:

F5C-2: Christina D Pedro MD ; Matthew V Buck MD; Ashraf S Habib MB BCh
Intracranial Injury in a Woman Presenting for Cesarean Delivery.
S2B-3: Christina D Pedro MD; Ashraf S Habib MB BCh; Remi Ojo BS; John Hunting MPH. Ketorolac 15 mg versus 30 mg for Analgesia Following Cesarean Delivery
S2D-3: Christina D Pedro MD; Ashraf S Habib MB BCh. Transversus Abdominis Plane Block for Ilioinguinal Nerve Entrapment Following Cesarean Delivery
S3B-4: Christina D Pedro M.D.; Ashraf S Habib MB BCh; Padma Gulur MD; Edmund Ong PhD; Chad A Grotegut MD; Brenna L Hughes MD. Postoperative Opioid Prescribing Practices Following Cesarean Delivery.
T1A-2: Christina D Pedro MD ; Ashraf S Habib MB BCh; Remi Ojo BS; John Hunting MPH. Effect of a Change in Analgesic Protocol on Postoperative Outcomes in Women Undergoing Cesarean Delivery.

Jennifer E. (Lee) Mehdiratta, MD

2016-2017
Jennifer E. (Lee) Mehdiratta, MD
Assistant Professor of Anesthesiology
Duke University Medical Center
Durham, North Carolina

Publications

Lane WE, Cobert J, Horres CR, Strouch Z, Mehdiratta J. (2019) “Undetected uterine rupture during induction of labor for intrauterine fetal demise using epidural anesthesia.” J Clin Anesth. 58:20-21. PMID: 31054522.
Ojo OA, Mehdiratta JE, Gamez BH, Hunting J, Habib AS. (2020) “Comparison of Programmed Intermittent Epidural Boluses with Continuous Epidural Infusion for the Maintenance of Labor Analgesia: A Randomized, Controlled, Double-Blind Study. Anesth Analg. 130(2): 426-435. PMID: 30882524.
Lee JE, George RB, Habib AS. Spinal-induced hypotension: Incidence, mechanisms, prophylaxis, and management: Summarizing 20 years of research. (2017) Best Pract Res Clin Anaesthesiol. 31(1):57-68. PMID: 28625306.

Abstract Presentations

Dominguez JE, Lee JE, Panchal V, Li YJ, Habib AS, Allen, TK. “Predictors of post-cesarean delivery pain in a prospective, randomized controlled trial of dexamethasone vs. placebo.” Society for Obstetric Anesthesia and Perinatology Annual Meeting, Bellevue, WA; May 2017.
Dominguez JE, Lee JE, Panchal V, Li YJ, Habib AS, Allen, TK. “Predictors of post-cesarean delivery pain in a prospective, randomized controlled trial of dexamethasone vs. placebo.” American Society of Anesthesiologists Annual Meeting, Boston, MA; October 2017.

Agnes M. Lamon, MD

2015-2016
Agnes M. Lamon, MD
Attending Anesthesiologist
University Medical Center of Princeton
Plainsboro, New Jersey

Publications

Lamon AM, Einhorn LM, Cooter M, Habib AS. (2017) “The impact of body mass index on the risk of high spinal block in parturients undergoing cesarean delivery: a retrospective cohort study. J Anesth. 31(4):552-558. PMID: 28421314.
Lamon AM, Habib AS. Managing anesthesia for cesarean section in the obese patient: current perspectives. (2016) Local and Regional Anesthesia. 16(9):45-57. PMID: 27574464.

Presented at SOAP 48th Annual Meeting, May 2016, Boston, MA:

SA-05: Agnes Lamon MD; Cathleen Peterson-Layne PhD, MD; Nicole Guinn MD; Mary Cooter MS; Aime Grimsely DNP; Geeta Swamy MD. Value of a Preoperative Anemia Clinic in a High-Risk Obstetric Population.
SA-77: Agnes Lamon MD; Ashraf Habib MD. Cesarean Delivery after Bilateral Orthotropic Lung Transplant and Acute Rejection.
SU-03: Angela X Li MD1 ; Agnes M Lamon MD2; Zaneta Strouch MD. Catastrophic Antiphospholipid Syndrome Presenting in the Puerperium Period.
SU-41: Agnes Lamon M. D.; Terrence Allen MD. TWO DIFFICULT AIRWAYS AT ONCE: EXIT procedure for severe fetal micrognathia in a mother with Pierre- Robin syndrome.

Amy A. Mauritz, MD

2014-2015
Amy A. Mauritz, MD
Attending Obstetric Anesthesiologist
St. Joseph’s Medical Center, Houston, Texas

Publications

Mauritz AA, Strouch ZY, Olufolabi AJ. (2016) A conundrum: General or neuraxial anesthesia and the use of ROTEM. Journal of Clinical Anesthesia. 32:159-61. PMID: 27290967.
Carter JE, Mauritz AA, Habib AS. Combination Antiemetics. In: Gan TJ, Habib AS (Eds), Postoperative nausea and vomiting: a practical guide. 1st Ed. Cambridge; Cambridge University Press 2016: 107-118.
Polin CM, Hale B, Mauritz AA, Habib AS, Jones CA, Strouch ZY, Dominguez JE. (2015) Anesthetic management of super-morbidly obese parturients for cesarean delivery with a double neuraxial catheter technique: a case series.” International Journal of Obstetric Anesthesia. 2015 Aug;24(3):276-80.
Mauritz AA , Dominguez JE, Guinn N, Gilner J, Habib AS. (2016) “Blood Conservation Strategies in a Blood Refusal Parturient with Placenta Previa and Placenta Percreta.” Anesthesia & Analgesia Case Reports. 6(5):111-3 PMID: 26556107.

Presented at the Society for Obstetric Anesthesiology and Perinatology Annual Meeting, May 2015, Boulder, CO:

Plethysmography variability index for prediction of spinal induced hypotension.
Reduction of Maternal Mortality in Ghana: Is an Obstetric Early Warning System the answer?
A Conundrum: General or neuraxial anesthesia and the use of ROTEM.
Blood conservation strategies in a blood refusal parturient with placenta previa and placenta percreta.

Carrie M. Polin, MD

2013-2014
Carrie M. Polin, MD
Assistant Professor
Division of Obstetric Anesthesia
The University of Tennessee at Knoxville

Publications- Fellowship Training

Polin C, Hale B, Jones CA, Strouch ZY, Dominguez JE. “Anesthetic management of super morbidly obese parturients for cesarean section using a double neuraxial catheter technique: A case series.” Society for Obstetric Anesthesia and Perinatology Annual Meeting, Toronto, Canada; May 2014.
Polin CM, Dominguez JE, Habib A. “A novel use of remifentanil for electroconvulsive therapy in a third trimester parturient.” Society for Obstetric Anesthesia and Perinatology Annual Meeting, Toronto, Canada; May 2014.
Ituk US, Habib AS, Polin CM, Allen TK. “Anesthetic management and outcomes of parturients with dilated cardiomyopathy in an academic centre.” Can J Anaesth. 2015 Mar;62(3):278-288. Epub 2014 Dec 11.
Polin CM, Hale B, Mauritz AA, Habib AS, Jones CA, Strouch ZY, Dominguez JE. (2015) Anesthetic management of super-morbidly obese parturients for cesarean delivery with a double neuraxial catheter technique: a case series.” International Journal of Obstetric Anesthesia. 2015 Aug;24(3):276-80.
Polin CM, Dominguez JE. (2015) “Combined intrathecal and epidural catheter for cesarean delivery in super morbidly obese parturients.” International Journal of Obstetric Anesthesia. 2015 Nov 12; EPub ahead of print.

Jennifer Dominguez, MD, MHS

2012–2013
Jennifer Dominguez, MD, MHS
Assistant Professor of Anesthesiology
Program Director, Obstetric Anesthesiology Fellowship Program
Duke University Medical Center

Publications – Fellowship Training

Crowgey TS, Dominguez JE, Peterson-Layne C, Allen TK, Muir HA, Habib AS. (2013) ³Retrospective assessment of the incidence of respiratory depression following neuraxial morphine administration for post-cesarean delivery analgesia.² Anesthesia and Analgesia.117(6):1368-1370.
Dominguez, JE and Habib, AS. (2013) Prophylaxis and treatment of the side effects of neuraxial morphine analgesia following cesarean delivery. Current Opinion in Anesthesiology. 26(3): 288-295.
Polin CM, Hale B, Mauritz AA, Habib AS, Jones CA, Strouch ZY, Dominguez JE. (2015) Anesthetic management of super-morbidly obese parturients for cesarean delivery with a double neuraxial catheter technique: a case series.” International Journal of Obstetric Anesthesia. 2015 Aug;24(3):276-80.
Crowgey TS, Dominguez JE, Peterson-Layne C, Allen TK, Muir HA, Habib AS. ³Retrospective assessment of the incidence of respiratory depression following neuraxial morphine administration for post-cesarean delivery analgesia.² American Society of Anesthesiologists Annual Meeting, San Francisco, CA; October 2013.
Dominguez JE, Mauritz AA, Lockhart E, Grotegut C, Small MJ and Allen T. ³Impact of an Obstetric Bleeding Protocol on Transfusion Practices and Coagulopathy in a Tertiary Care Medical Center.² American Society of Anesthesiologists Annual Meeting, San Francisco, CA; October 2013.
Dominguez JE, Gray L, Melnick A, Muir HA and Allen T. ³Anesthetic management of a parturient with cardiovascular and skeletal complications of Marfan syndrome for cesarean section.² American Society of Anesthesiologists Annual Meeting, San Francisco, CA; October 2013.
Polin C, Hale B, Jones CA, Strouch ZY, Dominguez JE. “Anesthetic management of super morbidly obese parturients for cesarean section using a double neuraxial catheter technique: A case series.” Society for Obstetric Anesthesia and Perinatology Annual Meeting, Toronto, Canada; May 2014.
Mauritz AA, Dominguez JE & Allen T. “Perioperative Management of Peripartum Hysterectomy at Duke University Hospital: A Retrospective Review. Society for Obstetric Anesthesia and Perinatology Annual Meeting, Toronto, Canada; May 2014.
Dominguez JE, Mauritz AA, Lockhart E, Grotegut C, Small MJ, & Allen T. “Impact of an Obstetric Bleeding Protocol on Post-operative Patient Outcomes in a Tertiary Care Medical Center.” Society for Obstetric Anesthesia and Perinatology Annual Meeting, Toronto, Canada; May 2014.
Polin CM, Dominguez JE, Habib A. “A novel use of remifentanil for electroconvulsive therapy in a third trimester parturient.” Society for Obstetric Anesthesia and Perinatology Annual Meeting, Toronto, Canada; May 2014.

Other Key Publications

Mauritz AA , Dominguez JE, Guinn N, Gilner J, Habib AS. (2016) “Blood Conservation Strategies in a Blood Refusal Parturient with Placenta Previa and Placenta Percreta.” Anesthesia & Analgesia Case Reports. 6(5):111-3 PMID: 26556107.
Polin CM, Dominguez JE. (2016) “Combined intrathecal and epidural catheter for cesarean delivery in super morbidly obese parturients.” International Journal of Obstetric Anesthesia. 25:89-90; PMID: 26718696.
Dominguez JE, Lockhart E, Miskovic A, Bullough AS. (2016) “Recognition of Obstructive Sleep Apnea in Pregnancy Survey.” International Journal of Obstetric Anesthesia. 14 Jan 2016. EPub ahead of print.
Jia S, Franz A, Dominguez JE, Habib AS. “The influence of obesity on post dural puncture headache following dural puncture with a Tuohy needle.” Society for Obstetric Anesthesia and Perinatology Annual Meeting, Colorado Springs; May 2015.
Dominguez JE, Ituk O, Habib AS. “Association between individual measures in three obstructive sleep apnea questionnaires and pregnancy outcomes” American Society of Anesthesiologists Annual Meeting, San Diego, CA; October 2015.
Dominguez JE, Lockhart E, Miskovic A, Bullough AS. “Recognition of Obstructive Sleep Apnea in Pregnancy: A SOAP Provider Survey” Society of Anesthesia and Sleep Medicine Annual Meeting, San Diego, CA; October 2015.
Thapa D, Dominguez JE. “Brugada Syndrome: Peri-operative Management for a Non-cardiac Case.” American Society of Anesthesiologists Annual Meeting, San Diego, CA; October 2015.
Plakke M, Franz A, Dominguez JE. “When Lightning Strikes Twice? Repeat Occurrence of Acute-Onset Horner’s Syndrome After Labor Epidural.” American Society of Anesthesiologists Annual Meeting, San Diego, CA; October 2015.

Grant and Awards

2014-2016: Duke Department of Anesthesiology Dream Innovation Grant
Obstructive Sleep Apnea in Pregnancy: Development of a Pregnancy-Specific Screening Tool (Role: PI)

August 2015 – 2018: NIH T32 Training Grant in Anesthesiology
(Role: Mentored Trainee)

2017-2019: SOAP Gertie Marx Research and Education Grant
Obstructive Sleep Apnea in Pregnant Women with Chronic Hypertension

Unyime Ituk, MD

2010–2011
Unyime Ituk, MD
Clinical Associate Professor of Anesthesia
Division Chief, Division of Obstetric Anesthesia
University of Iowa Health Care
Des Moines, IA

Publications – Fellowship Training

Habib AS, George RB, McKeen DM, White WD, Ituk US, Megalla SA, Allen TK: Antiemetics added to phenylephrine infusion during cesarean delivery: a randomized controlled trial.Obstet Gynecol 2013 May; 121(3):615-23
Ituk US, Allen TK, Habib AS: The peripartum management of a patient with glutaric aciduria type 1. J Clin Anesth 2013 Jan; 25(2):141-5
Ituk U, Constantinescu OC, Allen TK, Small MJ, Habib AS: Peripartum management of two parturients with ornithine transcarbamylase deficiency. Int J Obstet Anesth 2011 Dec; 21(1):90-3
Ituk U: Cardiomyopathy in pregnancy: Peripartum anesthetic management and review of outcomes in an academic center. American Society of Anesthesiologists 2011

Terrence Allen, MBBS, FRCA

2006–2007
Terrence Allen, MBBS, FRCA
Associate Professor of Anesthesiology
Duke University School of Medicine

Publications – Fellowship Training

Allen TK, RB George, White WD, Muir HA, Habib AS. A double-blind placebo controlled comparison of 4 fixed dose phenylephrine infusion regimens for hemodynamic support during spinal anaesthesia for caesarean Section. Presented as apart of the Gertie Marx research competition at the 40^th annual meeting of the Society of Obstetric Anesthesia and Perinatology, Chicago, May 2008.
Allen TK, George RB, AJ Olufolabi, James AH, Muir HA, Habib AS.The management of Cesarean delivery in a parturient with paroxysmal nocturnal hemoglobinuria complicated by severe preeclampsia. Can J Anesth 2007 54:646-651
Allen TK, Habib AS, Dear GL, White W, Lubarsky DA, Gan TJ. How much are patients willing to pay to avoid postoperative muscle pain associated with succinycholine? J Clin Anesth 2007;19(8):601-8.
Allen TK, George RB, Peterson-Layne C, Habib AS. Management of a parturient with an acute exacerbation of idiopathic pulmonary haemosiderosis and posterior spinal instrumentation. Br J Anaesth 2008;100(2):235-9.
Habib AS, George RB, Allen TK, Olufolabi AJ. A Pilot Study to Compare the Episure™ Autodetect™ Syringe with the Glass Syringe for Identification of the Epidural Space in Parturients. Anesth Analg 2008; 106: 541-543
George RB, Habib AS, Allen TK, Muir HA. A randomized controlled trial of Synera(R) versus lidocaine for epidural needle insertion in labouring parturients. Can J Anaesth. 2008;55(3):168-71.
Styron AG, George RB, Allen TK, Peterson-Layne C, Muir HA. Multidisciplinary management of placenta percreta complicated by embolic phenomena. Int J Obstet Anesth 2008;17:262-266.
Allen TK, Habib AS. P6 stimulation for the prevention of nausea and vomitingassociated with Cesarean delivery under neuraxial anesthesia: a systematic review of randomized controlled trials. Anesth Analg. 2008;107(4):1308-12.
George RB, Allen TK, Habib AS. Serotonin receptor antagonists for the prevention and treatment of pruritus, nausea and vomiting in women undergoing cesarean delivery with intrathecal morphine: a systematic review and meta-analysis. Anesth Analg. 2009 Jul;109(1):174-82.
Allen TK, Muir HA, George RB, Habib AS. A survey of the management of spinalinduced hypotension for scheduled caesarean. Int J Obstet Anesth 2009:18: 356 – 361
Allen TK, George RB, White WD, Muir HA, Habib AS.A double blind placebo controlled trial of four fixed doses of infusion regimens of phenylephrine for hemodynamic support during spinal anesthesia for cesarean delivery. Anesth Analg 2010;111:1221–9

Key Publications

Fink RJ, Allen TK, Habib AS. Remifentanil for Fetal Immobilization and Analgesia during The EXIT Procedure performed Under Combined Spinal-Epidural Anesthesia. Br J Anaesth 2011; 106 (6): 851–5. PMID: 21531744
Allen TK, Jones CA, Habib AS. Dexamethasone for the prophylaxis of postoperative nausea and vomiting associated with neuraxial morphine administration: A systematic review and meta-analysis. Anesth Analg 2012; 114(4):813-22. PMID: 22344239.
Ituk U, Constantinescu OC, Allen TK, Small MJ, Habib AS. Peripartum management of two parturients with ornithine transcarbamylase deficiency. Int J Obstet Anesth 2012 ;21(1):90-3. PMID: 22138526
Ituk US, Allen TK, Habib AS. The peripartum management of a patient with glutaric aciduria type 1. J Clin Anesth 2013;25(2)141-145. PMID: 23352788
George RB, Allen TK, Habib AS. Intermittent epidural bolus compared with continuous epidural infusions for labor analgesia: A systematic review and meta-analysis. Anesth Analg 2013;116 (1):133-44. PMID: 23223119.
Waldron NH, Jones CA, Gan TJ, Allen TK, Habib AS. Impact of perioperative dexamethasone on perioperative analgesia and side-effects: systematic review and meta-analysis. Br J Anaesth 2013;110(2):191-200. PMID: 23220857
Habib AS, George RB, McKeen DM, White WD, Ituk US, Megalla SA, Allen TK. Antiemetics added to phenylephrine infusion during cesarean delivery: A randomized controlled trial. Obstet Gynecol 2013;121(3):615-623 .PMID:23635626
Carr A, Kershaw T, Brown H, Allen T, Small M. Hypertensive disease in pregnancy: An examination of ethnic differences and the Hispanic paradox. J Neonatal Perinatal Med 2013; 6(1): 11-5. PMID: 24246453.
Crowgey TR, Dominguez JE, Peterson-Layne C, Allen TK, Muir HA, Habib AS. A Retrospective Assessment of the Incidence of Respiratory Depression After Neuraxial Morphine Administration for Postcesarean Delivery Analgesia. Anesth Analg 2013;117(6):1368-1370. PMID: 24257387
Allen TK, Feng L, Grotegut CA, Murtha AP. Progesterone Receptor Membrane Component 1 as the Mediator of the Inhibitory Effect of Progestins on Cytokine-Induced Matrix Metalloproteinase 9 Activity In Vitro. Reprod Sci. 2014; 21(2): 260-268. PMID: 23813454

Grants / Awards

7/2011 -7/2014. NIH/NIGMS T32 Integrated training in Anesthesiology Research (Role: Mentored Trainee)
1/2012-1/2014. Society for Obstetric Anesthesia and Perinatology/Gertie Marx research grant. Mechanisms of Progesterone mediated effects on cytokine induced Matrix Metalloproteinase activity in human trophoblast cells. Role: PI
Junior Faculty Receive Time, Training, and Mentorship through KL2 Awards

Ronald George, MD

2006–2007
Ronald George, MD
Professor of Clinical Anesthesia
Division Chief, Obstetric Anesthesia
University of California, San Francisco
San Francisco, CA

Publications – Fellowship Training

Allen TK, Habib AS, George RB, Muir HA. A survey of the management of spinal induced hypotension for scheduled cesarean delivery. International Journal of Obstetric Anesthesia, 2009; 18(4):356-361. PubMed ID:19734039.
George RB, Allen TK, Habib AS. Serotonin receptor antagonists for the prevention and treatment of pruritus, nausea, and vomiting in women undergoing cesarean delivery with intrathecal morphine: a systematic review and meta-analysis. Anesthesia and Analgesia, 2009; 109(1):174-182. PubMed ID: 19535708.
George RB, Kalich J, Yonish B, Murtha A. Apoptosis in the chorion of fetal membranes in preterm premature rupture of membranes. Am J Perinatol, 2008; 25(1):29-32. PubMed ID: 18075963.
George RB, Allen TK, Habib AS, Muir HA. Brief Report: A randomized controlled trial of Synera versus lidocaine for epidural needle insertion in laboring parturients. Canadian Journal of Anesthesia (CJA), 2008; 55(3):168-71. PubMed ID: 18310627.
Styron AG, George RB, Peterson-Layne C, Allen TK, Muir HA. Multidisciplinary management of placenta percreta complicated by a pulmonary embolism. Int J Obstet Anesth, 2008; 17(3):262-6. PubMed ID: 18501584.
Habib AS, George RB, Allen TK, Olufolabi AJ. A pilot study to compare the Episure Autodetect Syringe with the glass syringe for epidural catheter placement in parturients. Anesthesia and Analgesia, 2008; 106:541-3. PubMed ID: 18227314.
Allen TK, George RB, Peterson-Layne C, Habib AS. Management of a parturient with an acute exacerbation of Idiopathic Pulmonary Haemosiderosis and posterior spinal instrumentation. Br J Anesth, 2008; 100(2):235-9. PubMed ID: 18211996.
George RB, Melnick AH, Rose EC, Habib AS. Combined spinal epidural anesthesia for cesarean delivery and ex utero intrapartum treatment (EXIT) procedure: a report of three cases. Canadian Journal of Anesthesia (CJA), 2007; 54(3):218-22. PubMed ID: 17331934.
George RB, Olufolabi AJ, Muir HA. Critical arrhythmia associated with pulmonary artery catheterization in a parturient with severe pulmonary hypertension. Canadian Journal of Anesthesia (CJA), 2007; 54(6):486-7. PubMed ID: 17541080. Letter to the Editor.
Allen TK, George RB, Olufolabi AJ, James AH, Muir HA, Habib AS. The management of cesarean delivery in a parturient with paroxysmal nocturnal hemoglobinuria complicated by severe preeclampsia. Canadian Journal of Anesthesia (CJA), 2007; 54(8):646-51. PubMed ID: 17666718.

Key Publications

George RB, McKeen D, Andreou P, Habib A. A randomized, placebo-controlled trial of two doses of pregabalin for post-operative analgesia in women undergoing abdominal hysterectomy. Canadian Journal of Anesthesia (CJA), 2014 Mar 26. [Epub ahead of print]
George RB, Allen TK, Habib AS. Intermittent epidural bolus compared with continuous epidural infusions for labor analgesia: a systematic review and meta-analysis. Anesth Analg. 2013 Jan;116(1):133-44.
George RB, Munro A, Abdo I, McKeen DM, Lehmann C.. An observational assessment of the sublingual microcirculation of pregnant and non-pregnant women. Int J Obstet Anesth, 2013. PubMed ID: 24342223.
Habib AS, George RB, McKeen DM, White WD, Ituk US, Megalla SA, Allen TK. Antiemetics Added to Phenylephrine Infusion During Cesarean Delivery: A Randomized Controlled Trial. Obstetrics & Gynecology, 2013; 121 (3):615-23.IF 4.73: 2012 . PubMed ID: 23635626.
George RB, McKeen D, Chaplin AC, McLeod L.Up-down determination of the ED(90) of oxytocin infusions for the prevention of postpartum uterine atony in parturients undergoing Cesarean delivery. Can J Anaesth. 2010 Jun;57(6):578-82.
George RB, McKeen D, Columb MO, Habib AS. Up-down determination of the 90% effective dose of phenylephrine for the treatment of spinal anesthesia-induced hypotension in parturients undergoing cesarean delivery. Anesth Analg. 2010 Jan 1;110(1):154-8.

Grants / Awards

Canadian Anesthesiologists Society Career Scientist Award, 2011.
Society of Obstetric Anesthesia and Perinatology Zuspan Award for Collaborative Research with Obstetrics and Gynecology, 2007.
A Prospective Study of the Trajectory and Biopsychosocial Determinants of Postpartum Genito-pelvic Pain (Co-investigator): 2014/9 – 2017/9 Nova Scotia Health Research Foundation (NSHRF) Total Funding: $145,000 (Canadian dollar)
A Prospective Study of the Trajectory and Biopsychosocial Determinants of Postpartum Genito-pelvic Pain (Co-investigator): 2014/9 – 2016/9 CIHR-NSHRF RPP Total Funding: $227,364 (Canadian dollar)
Enhancing analgesia and anesthesia for women and high-risk pregnancies (Primary Investigator). 2011/6 – 2013/6 Canadian Anesthesiologists’ Society Total Funding: $120,000 (Canadian dollar)
A randomized, placebo controlled, multi-dose trial of pregabalin for postoperative pain in women undergoing an abdominal hysterectomy (Primary investigator):2008/4 – 2011/3 Nova Scotia Health Research Foundation (NSHRF), Total Funding: $115,269 (Canadian dollar)
Women’s & Obstetric Analgesia: 2008/7 – 2010/7 Recruitment & Establishment Grant, IWK Health Centre (Halifax, NS), Total Funding: $98,000

Other Achievements

Board of Directors – Kybele (2012-2014)
Kybele Team Leader – Tamale, Ghana (2008-2014)
Faculty – Anesthesia for Global Outreach Course (2008-2013)
Medical Director – Anesthesia for Global Outreach Course (2014)
Faculty – Canadian Anesthesiologist International Education Foundation – Kigali, Rwanda (2012-2014)

Abigail Melnick, MD

2004–2005
Abigail Melnick, MD
Assistant Professor of Anesthesiology
Duke University

Ashraf Habib, MD

2000–2001
Ashraf Habib, MD
Professor
Chief, Division of Women’s Anesthesia
Duke University

Publications – Fellowship Training

Deballi P, Habib A, Grocott H, Olufolabi A. Primary pulmonary hypertension: successful C/S using TIVA, NO, and TEE. Anesthesiology 2001; 94: A52.
Habib AS, Muir HA, Bell EA, Phillips-Bute BG, Reynolds JD. Magnesium sulfate and analgesic requirements following cesarean section. Anesthesiology 2001; 94: A87
Habib AS, Millar S, Deballi P 3^rd, Muir HA. Anesthetic management of a ventilator-dependent parturient with the King-Denborough syndrome. Canadian Journal of Anaesthesia 2003; 50(6): 589-92.
Habib AS, Helsley SE, Millar S, DeBalli III P, Muir HA. Anesthesia for Cesarean Section in a Patient With Spinal Muscular Atrophy. Journal of Clinical Anesthesia 2004; 16 (3): 217-19.

Other Publications

Habib A, Sharpe P, Anderson S, Francis S, Davidson AC, Smith G. Buscopan for the treatment of pain after laparoscopic sterilization. Anaesthesia 2001; 56 (2): 174-6.
Habib AS, Gan TJ. Combination therapy for postoperative nausea and vomiting- a more effective prophylaxis? Ambulatory surgery 2001; 9: 59-71.
Habib AS, Parker JL, Maguire AM, Rowbotham DJ, Thompsom JP. Effects of remifentanil and alfentanil on the cardiovascular responses to induction of anaesthesia and tracheal intubation in the elderly. British Journal of Anaesthesia 2002; 88 (3): 430-433.
Ng A, Habib A, Swami A, Smith G, Nunns D, Davidson AC. Randomized controlled trial investigating the effect of transcervical papaverine and bupivacaine on postoperative analgesia following laparoscopic sterilization. European Journal of Anaesthesiology 2002; 19(11): 803-7.
Habib AS, Gan TJ. Pharmacotherapy of postoperative nausea and vomiting. Expert Opinion on Pharmacotherapy 2003; 4(4): 457-73.
Habib AS, Gan TJ. Food and drug administration black box warning on the perioperative use of droperidol: a review of the cases. Anesthesia & Analgesia 2003; 96(5): 1377-9.
Breslin DS, Jiao K, Habib AS, Schultz J, Gan TJ. Pharmacodynamic interactions between cisatracurium and rocuronium. Anesthesia & Analgesia 2004; 98(1): 107-10.
Habib AS, El-Moalem HE, Gan TJ. The efficacy of the 5-HT (3) receptor antagonists combined with droperidol for PONV prophylaxis is similar to their combination with dexamethasone. A meta-analysis of randomized controlled trials. Canadian Journal of Anaesthesia 2004; 51(4): 311-9. (Published with an accompanying editorial).
Habib AS, Gan TJ. Evidence-based management of postoperative nausea and vomiting: A review. Canadian Journal of Anaesthesia 2004; 51(4): 326-41. (Published with an accompanying editorial).
Habib AS, White WD, Eubanks S, Pappas TN, Gan TJ. A Randomized Comparison of a Multimodal Management Strategy versus Combination Antiemetics for the Prevention of Postoperative Nausea and Vomiting. Anesthesia & Analgesia 2004; 99 (1): 77-81.
Habib AS, Muir HA, White WD, Spahn TE, Olufolabi AJ, Breen TW. Intrathecal morphine for analgesia after postpartum bilateral tubal ligation.
Anesthesia & Analgesia 2005; 100 (1): 239-43.
Habib AS, Gan TJ. The effectiveness of rescue antiemetics after failure of prophylaxis with ondansetron or droperidol: a preliminary report. Journal of Clinical Anesthesia 2005; 17 (1): 62-65.
Lacassie HJ, Millar S, Leithe LG, Muir HA, Montana R, Poblete A, Habib AS. Dural ectasia: a likely cause of inadequate spinal anesthesia in two parturients with Marfan’s syndrome. Brititish Journal of Anaesthesia 2005; 94 (4): 500-4.
Lacassie HJ, Muir HA, Millar S, Habib AS. Perioperative anesthetic management for cesarean section of a parturient with gestational diabetes insipidus. Canadian Journal of Anesthesia 2005; 52 (7): 733-6.
Habib AS, Itchon-Ramos N, Phillips-Bute BG, Gan TJ, The Duke Women’s Anesthesia Research Group. Transcutaneous acupoint electrical stimulation with the ReliefBand for the prevention of nausea and vomiting during and after cesarean section under spinal anesthesia. Anesthesia & Analgesia 2006; 102: 581-4.
Olufolabi AJ, Gan TJ, Laccasie HJ, White WD, Habib AS. A randomised, prospective double-blind comparison of the efficacy of generic propofol (sulfite additive) with Diprivan®. European Journal of Anaesthesiology 2006; 23 (4): 237-44.
Habib AS, Chen Y, Taguchi A, Hu HX, Gan TJ. Postoperative nausea and vomiting following inpatient surgeries in a teaching hospital: a retrospective database analysis. Current Medical Research and Opinion 2006; 22 (6): 1093-99.
Corbett WL, Reiter CM, Schultz JR, Kanter RJ, Habib AS. Anaesthetic Management of a Parturient with the Postural Orthostatic Tachycardia Syndrome: A Case Report. British Journal of Anaesthesia 2006; 97 (2): 196-9.
Habib AS, Gan TJ. The use of neostigmine in the management of acute postoperative pain and labour pain: a review. CNS Drugs 2006; 20 (10): 821-39.
Ho KY, Gan TJ, Habib AS. Gabapentin and postoperative pain- a systematic review of randomized controlled trials. Pain 2006; 126: 91-101.
Habib AS, Reuvini J, Taguchi A, White WD, Gan TJ. A Comparison of Ondansetron and Promethazine for the Treatment of Postoperative Nausea and Vomiting in Patients who Received Prophylaxis with Ondansetron: A Retrospective Database Analysis. Anesthesia & Analgesia 2007; 104 (3): 548-51.
George RB, Melnick AH, Rose EC, Habib AS. Case series: Combined Spinal Epidural anesthesia for cesarean delivery and ex utero intrapartum treatment (EXIT) procedure. Canadian Journal of Anesthesia 2007; 54: 218-22.
Habib AS, Muir HA, Schultz JR, Olufolabi AJ, White WD, Gan TJ. Postoperative Nausea and Vomiting Following the Use of Fentanyl or Remifentanil in Ambulatory Gynecologic Laparoscopic Surgery: A Prospective Randomized Trial. Ambulatory Surgery 2007; 13: 23-6.
Gan TJ, Apfel C, Kovac A, Philip B, Singla N, Minkowitz H, Habib AS, Knighton J, Carides AD, Zhang H, Horgan KJ, Evans JK, Lawson FC and the Aprepitant-PONV Study Group. A Randomized, Double-Blind Comparison of the NK1 Antagonist, Aprepitant, Versus Ondansetron for the Prevention of Postoperative Nausea and Vomiting. Anesthesia & Analgesia 2007; 104: 1082-9.
Gan TJ, Habib AS. Adenosine as a Non-Opioid Analgesic in the Perioperative Setting. Anesthesia & Analgesia 2007; 105: 487-494.
Allen TK, George RB, Olufolabi AJ, James AH, Muir HA, Habib AS. The management of cesarean delivery in a parturient with paroxysmal nocturnal hemoglobinuria complicated by severe preeclampsia. Canadian Journal of Anesthesia 2007; 54: 646-51.
Lacassie HJ, Habib AS, Lacassie HP, Columb MO. Motor blocking minimum local anesthetic concentrations of bupivacaine, levobupivacaine, and ropivacaine in labor. Regional Anesthesia and Pain Medicine 2007; 32 (4): 323-9.
Chen M, Habib AS, Panni MK, Schultz JR. Detecting infiltrated intravenous catheter using indigo carmine: a novel method. Anesthesia & Analgesia 2007; 105 (4): 1130-1.
Allen TK, Habib AS, Dear GL, While WD, Lubarsky DA, Gan TJ. How Much Are Patients Willing to Pay to Avoid Postoperative Muscle Pain Associated with Succinylcholine? Journal of Clinical Anesthesia 2007; 19 (8): 601-8.
Gan TJ, Meyer TA, Apfel CC, Chung F, Davis PJ, Habib AS, Hooper VD, Kovac A, Kranke P, Myles P, Philip BK, Samsa G, Sessler DI, Temo J, Tramer MR, Kolk CV, Watch M. Society for Ambulatory Anesthesia Guidelines for the Management of Postoperative Nausea and Vomiting (Special Article). Anesthesia & Analgesia 2007; 105 (6): 1615-28. (Published with an accompanying editorial).
D’Alonzo RC, White WD, Schultz JR, Jaklitsch PM, Habib AS. Ethnicity and the Distance to the Epidural Space in Parturients. Regional Anesthesia & Pain Medicine 2008; 33 (1): 24-9.
Benonis JG, Habib AS. Ex utero intrapartum treatment procedure in a patient with Arthrogryposis Multiplex Congenita using continuous spinal anesthesia and intravenous nitroglycerin for uterine relaxation. International Journal of Obstetric Anesthesia 2008; 17 (1): 53-6.
Allen TK, George RB, Perterson-Layne C, Habib AS. Management of a parturient with an acute exacerbation of Idiopathic Pulmonary Haemosiderosis and posterior spinal instrumentation for vaginal delivery with continuous spinal analgesia and BIPAP. British Journal of Anaesthesia 2008; 100 (2): 235-9.
Habib AS, George RB, Allen TK, Olufolabi AJ. A pilot study to compare the Episure Autodetect syringe with the glass syringe for identification of the epidural space in parturients. Anesthesia & Analgesia 2008; 106 (2): 541-3.
George RB, Habib AS, Allen TK, Muir HA. Brief Report: A randomized, controlled trial of SyneraÔ lidocaine for epidural needle insertion in laboring parturients. Canadian Journal of Anesthesia 2008; 55: 168-71.
Habib AS, Gan TJ. The use of droperidol before and after the Food and Drug Administration black box warning: A survey of the members of the Society of Ambulatory Anesthesia. Journal of Clinical Anesthesia 2008; 20 (1): 35-9.
Sun Y, Gan TJ, Dubose JW, Habib AS. Acupuncture and related techniques for postoperative pain: a systematic review of randomized controlled trials. British Journal of Anaesthesia 2008; 101 (2): 151-60.
Habib AS, White WD, ElGasim MA, Saleh G, Polascik TJ, Moul JW, Gan TJ. Transdermal nicotine for analgesia following radical retropubic prostatectomy. Anesthesia & Analgesia 2008; 107: 999-1004. (Published with an accompanying editorial).
Allen TK, Habib AS. P6 stimulation for the prevention of nausea and vomiting associated with cesarean delivery under neuraxial anesthesia: a systematic review of randomized controlled trials. Anesthesia & Analgesia 2008; 107 (4): 1308-12.
Habib AS, Minkowitz H, Osborn T, Ogunnaike B, Candiotti K, Viscusi E, Gu J, Creed MR, Gan TJ, the Adenosine Study Group. Phase 2 Double Blind Placebo Controlled Trial of Intravenous Adenosine for Perioperative Analgesia. Anesthesiology 2008; 109 (6): 1085-1091.
Habib AS, Wahl K, Gu J, Gan TJ, and the adenosine study group. Postoperative Pain outcomes after Vertical or Pfannenstiel Incision for Major Gynecologic Surgery. Current Medical Research and Opinion 2009 ;25 (6):1529-34.
Habib AS, Polascik TJ, Weizer AZ, White WD, Moul JW, ElGasim MA, Gan TJ. Lidocaine patch for analgesia following radical retropubic prostatectomy. Anesthesia & Analgesia 2009; 108 (6): 1950-3.
George RB, Allen TK, Habib AS. Serotonin receptor antagonists for the prevention and treatment of pruritus, nausea and vomiting in women undergoing cesarean delivery with intrathecal morphine: a systematic review and meta-analysis. Anesthesia & Analgesia 2009; 109 (1): 174-182.
Eckstrand JA, Habib AS, Williamson A, Horvath MM, Gattis KG, Kozart H, Ferranti J. Computerized surveillance of opioid-related adverse drug events in perioperative care: a cross-sectional study. Patient Saf Surg. 2009 Aug 11;3(1):18
D’Alonzo RC, Gan TJ, Moul JW, Albala DM, Polascik TJ, Robertson CN, Sun L, Dahm P, Habib AS. A Retrospective Comparison of Anesthetic Management of Robot Assisted Laparoscopic Radical Prostatectomy versus Radical Retropubic Prostatectomy. Journal of Clinical Anesthesia 2009; 21 (5): 322-8.
Allen TK, Muir HA, George RB, Habib AS. A survey of the management of spinal-induced hypotension for scheduled cesarean delivery. International Journal of Obstetric Anesthesia 2009; 18 (4): 356-61.
Gan TJ, Candiotti KA, Klein SM, Rodriguez Y, Nielsen KC, White WD, Habib AS. Double-blind comparison of granisetron, promethazine, or a combination of both for the prevention of postoperative nausea and vomiting in females undergoing outpatient laparoscopies. Canadian Journal of Anesthesia 2009; 56 (11): 829-36.
George RB, McKeen D, Columb MO, Habib AS. Up-down determination of the ED90 of phenylephrine for the treatment of spinal induced hypotension in parturients undergoing cesarean delivery. Anesthesia & Analgesia 2010; 110 (1): 154-8.
Auyong DB, Klein SM, Gan TJ, Roche AM, Olson D, Habib AS. Processed Electroencephalogram during Donation after Cardiac Death. Anesthesia & Analgesia 2010; 110 (5): 1428-32.
McCarthy CG, Megalla SA, Habib AS. Impact of Intravenous Lidocaine Infusion on Postoperative Analgesia and Recovery from Surgery: A Systematic Review of Randomized Controlled Trials. Drugs 2010; 70 (9): 1149-63.
Panni MK, George RB, Allen TK, Olufolabi AJ, Schultz JR, Okumura, M, Columb MO, Habib AS. Minimum effective dose of spinal ropivacaine with and without fentanyl for postpartum tubal ligation. International Journal of Obstetric Anesthesia 2010;19 (4):390-4.
Allen TK, George RB, White WD, Muir HA, Habib AS. A double blind placebo controlled trial of four fixed rate infusion regimens of phenylephrine for hemodynamic support during spinal anesthesia for cesarean delivery. Anesthesia & Analgesia 2010; 111 1221-1229. (Published with an accompanying editorial).
Fleming ND, Havrilesky LJ, Valea FA, Allen TK, Broadwater G, Bland A, Habib AS. Analgesic and antiemetic needs following minimally invasive vs. open staging for endometrial cancer. American Journal of Obstetrics and Gynecology. Am J Obstet Gynecol. 2011;204 (1):65.e1-6
Habib AS, Keifer JC, Borel CO, White WD, Gan TJ. A comparison of the combination of aprepitant and dexamethasone versus the combination of ondansetron and dexamethasone for the prevention of postoperative nausea and vomiting in patients undergoing craniotomy. Anesthesia & Analgesia 2011;112 (4):813-8.
Gan TJ, Gu J, Singla N, Chung F, Pearman MH, Bergese SD, Habib AS, Candiotti KA, Mo Y, Huyck S, Creed MR, Cantillon M; for the Rolapitant Investigation group. Rolapitant for the Prevention of Postoperative Nausea and Vomiting: A Prospective, Double-Blinded, Placebo-Controlled Randomized Trial. Anesthesia & Analgesia 2011;112 (4):804-812. (Published with an accompanying editorial).
Fink RJ, Allen TK, Habib AS.  Remifentanil for Fetal Immobilization and Analgesia during EXIT Procedure Under Combined Spinal-Epidural Anesthesia. British Journal of Anaesthesia 2011; 106 (6):851-5.
McQueen-Shadfar LA, Megalla SA, White WD, Olufolabi AJ, Jones CA, Habib AS. Impact of intraoperative dexmedetomidine on postoperative analgesia following gynecologic surgery. Current Medical Research and Opinion 2011; 27 (11): 2091-7
Ituk U, Constantinescu O, Allen TK, Small NJ, Habib AS. Peripartum management of two parturients with ornithine transcarbamylase deficiency. International Journal of Obstetric Anesthesia 2012; 21 (1):90-3
Habib AS. A Review of the impact of phenylephrine administration on maternal hemodynamics and maternal and neonatal outcomes in women undergoing cesarean delivery under spinal anesthesia. Anesthesia & Analgesia 2012; 114 (2): 377-90
Mishriky B, Habib AS. Metoclopramide for Nausea and Vomiting Prophylaxis during and after Caesarean Delivery: A Systematic Review and Meta-analysis. British Journal of Anaesthesia 2012; 108 (3): 374-83 (Published as CME material)
Allen TK, Jones CA, Habib AS. Dexamethasone for the Prophylaxis of Postoperative Nausea and Vomiting Associated with Neuraxial Morphine Administration: A Systematic Review and Meta-analysis. Anesthesia & Analgesia 2012; 114 813-822
Klinger RY, White WD, Hale B, Habib, AS, Bennett-Guerrero E. Hemodynamic Impact of Dexmedetomidine Administration in 15,656 Non-Cardiac Surgical Cases. Journal of Clinical Anesthesia 2012 ; 24 (3): 212-20.
Mishriky BM, George RB, Habib AS. Transversus abdominis plane block for analgesia after Cesarean delivery: a systematic review and meta-analysis. Canadian Journal of Anesthesia 2012; 59 (8); 766-78.
Sun Y, Habib AS, Wenger T, Gratz I, Glick D, Adsumelli R, Creed M, Gan TJ. The Effects of Dose Ranging Adenosine Infusion on electrocardiographic findings during and after General Anesthesia. Journal of Anesthesia 2012; 26: 689-95
Macleod DB, Habib AS, Ikeda K, Spyker D, Cassella JV, Ho KY, Gan TJ. Inhaled Fentanyl Aerosol in Healthy Volunteers: Pharmacokinetics and Pharmacodynamics. Anesthesia & Analgesia 2012; 115; 5: 1071-7.
George RB, Allen TK, Habib AS. Intermittent epidural bolus compared to continuous epidural infusions for labor analgesia: A systematic review and meta-analysis. Anesthesia & Analgesia 2013; 116 (1): 133-44.
Ituk US, Allen TK, Habib AS. The peripartum management of a patient with glutaric aciduria type 1. Journal of Clinical Anesthesia 2013; 25(2): 141-5.
Bolac CS, Wallace AH, Broadwater G, Havrilesky LJ, Habib AS. Impact of postoperative nausea and vomiting prophylaxis with dexamethasone on postoperative wound complications in patients undergoing laparotomy for endometrial cancer. Anesthesia & Analgesia 2013; 116 (5):1041-7 (published with an accompanying editorial).
Waldron N, Jones CA, Allen TK, Gan TJ, Habib AS. Impact of Perioperative Dexamethasone on Postoperative Analgesia and Side Effects of its Administration: A Systematic Review and Meta-Analysis. British Journal of Anaesthesia 2013 Feb; 110 (2): 191-200 (published as CME material)
Habib AS, George RB, McKeen DM, White WD, Ituk US, Megalla SA, Allen TK. Antiemetics added to phenylephrine infusion during cesarean delivery: a randomized controlled trial. Obstetrics and Gynecology 2013; 121 (3): 615-623.
Crowgey TR, Dominguez JE, Peterson-Layne CL, Allen TK, Muir HA, Habib AS. Retrospective assessment of the incidence of respiratory depression following neuraxial morphine administration for post-cesarean delivery analgesia. Anesthesia & Analgesia 2013; 117 (6): 1368-70.
Gan TJ, Diemunsch P, Habib AS, Kovac A, Kranke P, Meyer T, Watcha M, Chung F, Angus S, Apfel CC, Bergese S, Candiotti K, Chan M, Davis PJ, Hooper V, Lagoo S, Myles P, Nezat G, Philip B, Tramèr MR. SAMBA Consensus guidelines for the management of postoperative nausea and vomiting. Anesthesia & Analgesia 2014; 118 (1): 85-113.
Gan TJ, Habib AS, Miller TE, White W, Apfelbaum JL. Incidence, patient satisfaction, and perceptions of post-surgical pain: results from a US national survey. Current Medical Research and Opinion 2014; 30 (1): 149-60.
Mishriky BM, Habib AS. Nicotine for postoperative analgesia: a systematic review and meta-analysis. Anesthesia & Analgesia 2014; 119: 268–75 (Published with an accompanying editorial)
Yang K, Habib AS, Lu M, Branch MS, Manberg P, Sigl JC, Gan TJ. A prospective evaluation of the incidence of adverse events in nurse-administered moderate sedation guided by sedation scores or bispectral index. Anesthesia & Analgesia 2014; 119(1): 43-48.
Habib AS, Moul JW, Polascik TJ, Robertson CN, Roche AM, White WD, Hill SE, Nosnick I, Gan TJ, Duke Perioperative Outcome Study Group. Low Central Venous Pressure versus Acute Normovolemic Hemodilution versus Conventional Fluid Management for Reducing Blood Loss in Radical Retropubic Prostatectomy: A Randomized Controlled Trial. Current Medical Research and Opinion 2014; 30 (5): 937-43.
George RB, McKeen DM, Andreou P, Habib AS. A randomized placebo-controlled trial of two doses of pregabalin for postoperative analgesia in patients undergoing abdominal hysterectomy. Canadian Journal of Anesthesia 2014; 61 (6): 551-7.
Hale B, Habib AS. Sheehan’s syndrome: acute presentation with severe headache. International Journal of Obstetric Anesthesia 2014; 23: 383-6
Mishriky BM, Waldron N, Habib AS. Impact of Pregabalin on Acute and Persistent Postoperative Pain: a Systematic Review and Meta-Analysis. British Journal of Anaesthesia 2015; 114: 10-31. (published as CME material)
Ituk U, Habib AS, Polin CM, Allen TK. Anesthetic Management and Outcomes of Parturients with Dilated Cardiomyopathy in an Academic Center. Canadian Journal of Anesthesia 2015 ;62 (3):278-288
Strouch ZY, Dakik CG, White WD, Habib AS. Anesthetic Technique for Cesarean Delivery and Neonatal Acid-Base Status: A Retrospective Database Analysis. International Journal of Obstetric Anesthesia 2015; 24: 22-9
Polin CM, Hale B, Mauritz AA, Habib AS, Jones CA, Strouch ZY, Dominguez JE. Anesthetic management of super morbidly obese parturients for cesarean delivery with a double neuraxial catheter technique: a case series. International Journal of Obstetric Anesthesia 2015; 24: 276-80
Turner TB, Habib AS, Broadwater G, Valea FA, Fleming ND, Ehrisman JA, Di Santo N, Havrilesky LJ. Postoperative pain scores and narcotic use in robotic-assisted versus laparoscopic hysterectomy for endometrial cancer staging. Journal of Minimally Invasive Gynecology 2015: 22 (6): 1004-10.
Sultan P, Habib AS, Cho Y. Carvalho B. The Effect of Patient Warming during Caesarean Delivery on Maternal and Neonatal Outcomes: A meta-analysis. British Journal of Anaesthesia 2015 ;115 (4):500-10
Zaphiratos V, George RB, Boyd C, Habib AS. Exteriorization compared to in situ uterine repair for cesarean delivery: a systematic review and meta-analysis. Canadian Journal of Anesthesia 2015; 62 (11): 1209-1220
Mauritz A, Dominguez JE, Guinn N, Gilner J, Habib AS. Blood conservation strategies in a blood refusal parturient with placenta previa and placenta percreta. Anesthesia & Analgesia Case Reports 2015 (Epub ahead of print)
Low Y, White WD, Habib AS. Postoperative hyperglycemia after 4 vs. 8-10 mg dexamethasone for postoperative nausea and vomiting prophylaxis in patients with type II diabetes mellitus: a retrospective database analysis. Journal of Clinical Anesthesia 2015; 27(7): 589-94
Merk B, Havrilesky LJ, Ehrisman JA, Broadwater G, Habib AS. Impact of Postoperative Nausea and Vomiting Prophylaxis With Dexamethasone on the Risk of Recurrence of Endometrial Cancer. Current Medical Research and Opinion 2015; 19: 1-19
Tien M, Peacher DF, Franz AM, Jia S, Habib AS. Failure rate and complications associated with the use of spinal catheters for the management of inadvertent dural puncture in the parturient: a retrospective comparison with re-sited epidural catheters. . Current Medical Research and Opinion 2016 Jan 28:1-23. [Epub ahead of print].
Adesope OA, Einhorn LM, Olufolabi AJ, Cooter M, Habib AS. The Impact of gestational age and fetal weight on the risk of failure of spinal anesthesia for cesarean delivery. International Journal of Obstetric Anesthesia (In press).
Ituk U, Cooter M, Habib AS. Retrospective comparison of ephedrine and phenylephrine for the treatment of spinal anesthesia induced hypotension in preeclamptic patients. Current Medical Research and Opinion (In press).

Grants / Awards

Title: Analgesia following retropubic prostatectomy.
Name of Award: Duke University Clinical Research Award
Start date: 01/2004
End date: 12/2006

Title: A randomized, double-blind, placebo-controlled, dose-response trial of intravenous adenosine for perioperative analgesia in females undergoing total abdominal hysterectomy or myomectomy.
Funding source: Xsira pharmaceuticals.
Start date: 10/01/2005
End date: 09/30/2006

Title: A comparison of the combination of aprepitant and dexamethasone versus the combination of ondansetron and dexamethasone for the prevention of postoperative nausea and vomiting in patients undergoing craniotomy.
Funding source: Merck and Co.
Start date: 06/06/2007
End date: 06/06/2009

Title: A Randomized, Double- Blind, Double- Dummy, Dose- Ranging, Active- and Placebo- controlled Study of Single- Dose Oral Rolapitant Monotherapy for the Prevention of Postoperative Nausea and Vomiting (PONV)
Funding source: Schering-Plough research institute.
Start date: 10/01/2007
End date: 09/30/2008

Title: “Effect of the Perioperative Use of Dexmedetomidine in Conjunction with General Anesthesia on Postoperative Analgesia and Early Recovery Following Surgery.”
Funding source: Hospira.
Start date: 10/03/2008
End date: 10/02/2010

Title: Computerized Surveillance of opioid related adverse effects in the perioperative period.
Funding source: Anesthesia Patient Safety Foundation
Start date: 01/01/2010
End date: 06/30/2012

Title: Identification of Predictors for severe acute pain and persistent pain after breast surgery.
Funding Source: Society for Ambulatory Anesthesia
Start date: 07/01/2012
End date: 06/30/2014

Title: DP10017-Randomized, double-blind, placebo-controlled Phase III study of APD421 (amisulpride for IV injection) as combination prophylaxis against post-operative nausea and vomiting in high –risk patients
Funding Source: Acacia Pharma
Start date: 03/01/2015
End date: 02/28/2018

Title: DP10018- Randomized, double-blind, placebo-controlled study of APD421 (amisulpride for IV injection) as treatment of established post-operative nausea and vomiting, in patients who have had no prior prophylaxis
Funding Source: Acacia Pharma
Start date: 12/01/2015
End date: 11/30/2016

Other Achievements

Participant in Kybele outreach trip to Croatia (2005) and Romania (2012)
Team leader for Kybele Outreach trips to Egypt (2008 & 2009)
Chair of SOAP International Outreach Committee (2008-to date)
Chair of ASA abstract review subcommittee on Obstetric Anesthesia and Perinatology (2013- to date)
Chair of SAMBA Scientific Papers Committee (2014-to date)

Ellen Lockhart, MD

1997–1998
Ellen Lockhart, MD
Professor and Vice Chair
Washington University
Saint Louis, MO

Publications from Fellowship

Hilton ABR, Lockhart EM, Penning DH. Epidural analgesia in parturients with previous spinal irradiation. Canadian Journal of Anaesthesia, 45:884-887, 1998.
Lockhart EM, Penning DH, Olufolabi AJ, Bell EA, Booth JV, Kern FH. SV02 Monitoring during Spinal Anesthesia and Cesarean Section in a Parturient with Severe Cyanotic Congenital Heart Disease. Anesthesiology, 90(4):1213-1215, 1999 .
Booth JV. Lindsay DR. Olufolabi AJ. El-Moalem HE. Penning DH. Reynolds JD and The Duke Women’s Anesthesia Research Group (Bell, EA, Dwane, PD, Lockhart, EM, Maroof, MM, Spahn, TE) Subarachnoid meperidine (Pethidine) causes significant nausea and vomiting during labor. Anesthesiology. 93(2):418-21, 2000.
Lockhart EM, Warner DS, Pearlstein R, Penning DH, Mehrabani, S, Boustany, R-M, Allopregnanolone Attenuates NMDA-Induced Excitotoxicity and Apoptosis in the Human NT2 Cell Line in Culture, Neurosci Lett, 328(1):33-36, 2002.
Sumeer Dhar, Rhonda L. Bitting, Svetlana N. Rylova, Paul J. Jansen, Ellen M. Lockhart, Dwight D. Koeberl, Andrea Amalfitano and Rose-Mary N. Boustany Flupirtine blocks apoptosis in Batten patient lymphoblasts and in human post-mitotic,CLN3-and CLN2-deficient neurons. Ann Neurol, (4):448-66, 2002.

Oral Presentations from Fellowship

Does progesterone protect the fetal brain?, Annual Society for Obstetric Anesthesia and Perinatology Meeting, Vancouver, CANADA-April1998
Progesterone as an Endogenous Neuroprotectant, 1998 North Carolina Society of Anesthesiologists- Fellows Research Presentation, Myrtle Beach, SC- September 1998

Key Publications

Lockhart EM, Baysinger CL. Intracranial Venous Thrombosis in the Parturient. Anesthesiology. (4):652-8, 2007.
Leighton BL, Wall MH, Lockhart EM, Phillips LE, Zatta AJ. Use of Recombinant Factor Vlla in Patients with Amniotic Fluid Embolism: A Systematic Review of Case Reports. Anesthesiology. 2011 Jun 30 [Epub ahead of print]
Baysinger CL, Pope JE, Lockhart EM, Mercaldo ND., The Management of Accidental Dural Puncture and Postdural Puncture Headache: A North American Survey. J Clin Anesth. 2011 Aug;23(5):349-60. Epub 2011 Jun 22.
Nissman KW, Nissman DB, Leighton BL, Varaday SS, Lockhart EM. Necrotizing Fasciitis after Cesarean Delivery. Anesthesiology. 2011 Dec;115(6):1301.
Lockhart EM, Willingham MD, Abdallah AB, Helsten DL, Bedair BA, Thomas J, Duntley S, Avidan MS. Obstructive sleep apnea screening and postoperative mortality in a large surgical cohort. Sleep Med. 2013 May;14(5):407-15. Epub 2013 Mar 13.
Young JL, Lockhart EM, Baysinger CL. Anesthetic and obstetric management of the opioid-dependent parturient. Int Anesthesiol Clin. 2014 Spring;52(2):67-85.
Lockhart EM, Ben Abdallah A, Tuuli MG, Leighton BL. Obstructive Sleep Apnea in Pregnancy: Assessment of Current Screening Tools. Obstet Gynecol. 2015 Jul;126(1):93-102.
Dominguez JE, Lockhart EM, Miskovic A, Bullough AS. Recognition of obstructive sleep apnea in pregnancy survey. Int J Obstet Anesth. 2016 Jan 14. pii: S0959-289X(16)00024-8. [Epub ahead of print]

Grants / Awards

Duke University Medical Center, 1998
Department of Anesthesiology Academic Evening
Post-Doctoral Laboratory Award
Second Runner-Up

Duke University Medical Center, 2000
Department of Anesthesiology Academic Evening
Post-Doctoral Laboratory Award
Runner-Up

Co-PI, NIH Integrated Training in Anesthesiology Research, ($40,000), Duke
University Medical Center; PI David Warner, MD; 70% effort, 1997- 2000

Foundation for Anesthesia Education and Research (FAER) – New Investigator Award – ($70,000), 1999-2001