Duke Anesthesiology Clinical Research Unit (CRU) Group - 2023


To provide our patients with the opportunity to participate in innovative clinical research. Following Good Clinical Practice guidelines, Duke’s Clinical Research Unit (CRU) provides optimum staff coverage to meet protocol timelines within budget.

About Us

The Clinical Research Unit (CRU), formerly known as Clinical Anesthesiology Research Endeavors (CARE), is a departmental initiative to further organize our clinical research efforts in all areas of anesthesia and perioperative research at Duke University Medical Center and its affiliated sites. It began as an organization in 1999. After achieving great success in the cardiothoracic and critical care medicine divisions, the unit officially launched in January of 2003. The CRU is composed of an extensive network of investigators, clinical research support staff, biostatistics staff, perioperative and outcomes database staff, and business development staff.

The department has an outstanding reputation in clinical research, focused in the areas of postoperative nausea and vomiting prevention, preservation of cognitive function after surgery, transesophageal echocardiography, role of inflammation in clinical outcome, intravenous fluids, hemodilution and blood substitutes, hemodynamic monitoring, genetics and outcome, organ protection during surgery, pain management, regional anesthesia and clinical pharmacology. This research has led to changes in clinical practice and has improved outcomes for patients after cardiac and non-cardiac surgery.

Meet the Team

Kamrouz Ghadimi, MD, MHSc

Kamrouz Ghadimi, MD, MHSc
Director, Clinical Research Unit
Associate Professor of Anesthesiology

Anne D. Cherry, MD

Anne D. Cherry, MD
Assistant Director, Clinical Research Unit
Assistant Professor of Anesthesiology

Bonnie Funk, BSN, RN, CCRP

Bonnie Hilliard, BSN, RN, CCRP
Research Practice Manager

Alicja Szydlowska, BS, MBA, CCRC

Alicja Schultz, BS, MBA, CCRC
Assistant Research Practice Manager

Financial Practice Manager

Tammy Kim, MA, CRA, AGM, RAA

Research Program Leader, Senior

Vincent Anani, MPH

Research Program Leader

Bethany Hsia, PhD

Clinical Research Nurse Coordinator, Senior

Kelly Rodden, BSN, RN

Clinical Research Nurse Coordinator

Carrie Schlabaugh, BSN, RN

Clinical Research Specialist, Senior

Stratton Barth, BS
Michael Bennett, BS
Rachele Brassard, BSW
Morgan DePrizio, BS
Reid Funderburk, BS
Nia Hammett, MBS
Sloan Soyster Heinz, BS
Shivangi Jha, BS
Luar Mercado Lopez, BS
Michael Miller, BA
Kiliejah Moore, BS
Yanni-Taylor Shaw, BS
Cole Shumate, BA
Harper Wilkinson, BA
Angelina Xiong, BA

Clinical Research Coordinator, Senior

Omowunmi Olaleye, MS, CCRP
Yanne Toulgoat-Dubois, BA

Clinical Research Coordinators

Megan Beyer, MS, RD, LDN
Piper Boykin, BS
Taylor Brown, MS
Ashley Burke, BS, CCRC
Morgan Caldwell, BS
Nancy "Meg" Hardesty, BA
Chelsea Hignite, BS
Lila Kongmany, BS
Janice Lim, BS
Amy Patrylick, BA
Erick Lorenzana-Saldivar, BS
Emmalee Metzler, BA, CCRP
Sharon Norman
Christy Peterson, AAS, BS
Courtney Holland Stanczak, BS
Noah Timko, MPH, CCRC
Joshua Wynn, BS

Statistical Support

Yi-Ju Li, PhD, Program Leader, Biostatistics and Clinical Outcomes
Mary Cooter Wright, MS, Biostatistician III
Matthew Fuller, MS, Biostatistician II
Morgan Rosser, MS, Biostatistician II
Jane La, MS, Biostatistician II

The principles that guide us are:

  1. Quality Improvement.
  2. Improving outcomes for patients by improving clinical practice through clinical research.
  3. Improving medical practices by sharing knowledge gained through scholarly publications.

Project Planning and Startup

  • Coordination with Industry Staff
  • Recruit Investigators


  • Randomize patients from caseload
  • Coordinate with study monitor
  • Strict adherence to study protocol


  • Coordination with Industry Statistical Plan
  • Interim Analysis available


  • Ensured followup of all queries
  • Longitudonal followup available


  • Presentation at National and International Scientific Meetings
  • Manuscript preparation with industry review
  • Neurological Outcomes in Cardiac, Thoracic and Medical Patients.
  • Investigational Cardiopulmonary Bypass lab providing pre-clinical support for neurological outcomes research.
  • Role of Inflammation in Affecting Clinical Outcome.
  • Perioperative Organ Protection.
  • Brain Protection in Cardiac and Thoracic Surgery.
  • Preservation of Heart Function.
  • Blood Substitutes.
  • Minimally Invasive Surgery and Off Pump Cardiac Surgery.
  • Transesophageal Echocardiography (TEE).
  • Renal Protective Strategies.
  • Molecular Biology.
  • Genetics of Perioperative Outcomes (Genomics).
  • Medical Economic Assessments of Interventions in Cardiothoracic Surgery.
  • Perioperative Control of Nausea and Vomiting
  • Perioperative Control of Pain
  • Pediatric Drug Development
  • Anesthesia and Postoperative Cognitive Decline