The following departmental faculty were awarded new competitive and non-competitive research grants (of $100,000 +) during calendar year 2022.
Niccolò Terrando, BSc, DIC, PhD
Microglia-Amyloid Interactions in Delirium Superimposed on Dementia
Award Date: 12/26/2022
Funding Agency: National Institutes of Health/National Institute on Aging
Grant Amount: $4,311,630
Shad Smith, PhD
Single-Cell Omics Approaches to Investigate TMD
Award Date: 10/21/2022
Funding Agency: NIH/National Institute of Dental and Craniofacial Research
Grant Amount: $402,487
Madan M. Kwatra, PhD
Biomarker study of NCT05038982
Award Date: 10/19/22
Funding Agency: Johns Hopkins University
Wei Yang, PhD, FAHA
Targeted Neuromodulation to Enhance Recovery of the Aged Brain After Ischemic Stroke
Award Date: 10/13/22
Award Type: R21
Funding Agency: NIH/National Institute of Neurological Disorders and Stroke (NINDS)
Grant Amount: $442,750
Christopher R. Donnelly, DDS, PhD
Neural Architecture of the Murine and Human Temporomandibular Joint
Award Date: 10/13/22
Funding Agency: National Institutes of Health
Grant Amount: $5,734,530
Leah Acker, MD, PhD
The Role of the Aging Brain-Heart-Immune Axis in Postoperative Delirium
Award Date: 10/12/2022
Award Type: R03
Funding Agency: National Institutes of Health
Grant Amount: $322,000
Miriam M. Treggiari, MD, PhD, MPH
Randomized Trial of Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia - Prevent 2 Study
Award Date: 9/30/22
Funding Agency: National Institutes of Health
Grant Amount: $743,776
Thomas Van de Ven, MD, PhD
Single Nucleus Expression Profiling of Human Sciatic Nerve after Traumatic Amputation: Predicting Pain and Functional Outcomes
Award Date: 9/22/22
Funding Agency: Department of Defense
Grant Amount: $1,426,733
Katherine Martucci, PhD
Neurobiological Consequences of Long-Term Opioid Therapy in the Brain and Spinal Cord
Award Date: 9/20/2022
Award Type: R01
Funding Agency: National Institutes of Health
Grant Amount: $3,195,387
Christopher R. Donnelly, DDS, PhD, Shad Smith, PhD
Sexually Dimorphic Pain Signaling Mechanisms
Award Date: 9/14/22
Funding Agency: National Institutes of Health
Grant Amount: $2,132,329
Niccolò Terrando, BSc, DIC, PhD
Immunovascular Interactions in Postoperative Delirium Superimposed on Dementia (DSD)
Award Date: 9/14/22
Funding Agency: National Institutes of Health
Grant Amount: $2,244,681
Sven-Eric. Jordt, PhD
Nicotine Pouches: Chemical Composition, Toxicity and Behavioral Effects of a New Tobacco Product Category
Award Date: 9/2/22
Funding Agency: National Institutes of Health
Grant Amount: $416,512
Satyanarayana Achanta, DVM, PhD, Sven-Eric. Jordt, PhD
Pulmonary Cell Fate and Lung Repair in Rodent and Porcine Models of Chlorine and Phosgene Inhalation Injuries
Award Date: 9/2/2022
Award Type: R01
Funding Agency: NIH/National Institute of Environmental Health Sciences
Grant Amount: $1,430,370
Heath Gasier, PhD
The Role of GABA in Susceptibility to Oxygen Toxicity with Repeated HB02 Exposure
Award Date: 9/2/2022
Funding Agency: Office of Naval Research
Grant Amount: $844,714
Christopher R. Donnelly, DDS, PhD
Neuro-Immune Modulation of Pain in Health and Disease
Award Date: 9/2/2022
Award Type: R01
Funding Agency: National Institutes of Health
Grant Amount: $3,311,196
Melissa E. Bauer, DO
Large-scale Implementation of Community Co-led Maternal Sepsis Care Practices to Reduce Morbidity and Mortality from Maternal Infection
Award Date: 9/2/22
Funding Agency: National Institutes of Health
Grant Amount: $764,502
Christopher R. Donnelly, DDS, PhD
Identifying Non-Opioid Strategies to Manage Oral Cancer Pain
Award Date: 9/1/2022
Funding Agency: University of Michigan
Paul E. Wischmeyer, MD, EDIC, FASPEN, FCCM
Personalized Targeted Nutrition via StructurEd Nutrition Delivery Pathway to Improve Recovery of Physical Function in Trauma - SeND Home
Award Date: 8/30/2022
Funding Agency: Department of Defense
Grant Amount: $2,203,452
David S. Warner, MD
Integrated Training in Anesthesiology Research
Award Date: 8/18/22
Funding Agency: National Institutes of Health
Grant Amount: $1,435,120
Luis Ulloa, PhD, MS, Wei Yang, PhD, FAHA
Vagal Control of Tissue SUMOylation as a Novel Anti-Inflammatory Target in IBD
Award Date: 7/28/22
Funding Agency: National Institutes of Health
Grant Amount: $442,750
Jamie R. Privratsky, MD, PhD
Novel Mitochondrial Protective Properties of Annexin A1
Award Date: 7/28/22
Funding Agency: National Institutes of Health
Grant Amount: $1,288,000
Andrea G. Nackley, PhD
Defining the Role of Peripheral Adrb3 in Chronic Pain and Inflammation
Award Date: 7/28/22
Funding Agency: National Institutes of Health
Grant Amount: $1,039,036
Ru-Rong Ji, PhD
Pain Management in Critical Combat Casualty Environments using Resorbable Poly(ester urea) Films for Sustained Delivery of Meloxicam and Bupivacaine
Award Date: 7/28/22
Funding Agency: Department of Defense
Grant Amount: $1,517,530
Ru-Rong Ji, PhD
Developing Non-Opiate GPCR Signaling Biased Agents for Pain Management
Award Date: 7/28/22
Funding Agency: Department of Defense
Grant Amount: $1,608,140
Satyanarayana Achanta, DVM, PhD
Inhibition of Soluble Epoxide Hydrolase Protects Against Phosgene-Induced Lung Injuries
Award Date: 7/27/22
Funding Agency: National Institutes of Health
Grant Amount: $201,250
Miles Berger, MD, PhD
Low Neurophysiologic Resistance to Anesthetics as a Marker of Preclinical/Prodromal Alzheimer's Disease and Neurovascular Pathology, Delirium Risk and Inattention
Award Date: 7/26/22
Funding Agency: National Institutes of Health
Grant Amount: $3,544,768
Joseph P. Mathew, MD, MHSc, MBA
Neurocognition and Greater Maintenance of Sinus Rhythm in AF (NOGGIN AF)
Award Date: 7/17/22
Funding Agency: National Institutes of Health
Grant Amount: $2,998,997
Jorn A. Karhausen, MD
Mast cell activation as a determinant of neurologic injury after cardiac arrest
Award Date: 7/14/22
Funding Agency: National Institutes of Health
Grant Amount: $199,062
Miles Berger, MD, PhD
APOE4 dependent regulation of CSF Complement Pathway Activation in the development of Alzheimer's Disease
Award Date: 7/11/22
Funding Agency: National Institutes of Health
Grant Amount: $3,802,670
Madan M. Kwatra, PhD
Prurigo Nodularis: Disease Burden and Rationale for Novel Therapeutics
Award Date: 7/5/22
Funding Agency: Galderma
Andrea G. Nackley, PhD
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments (Vestibulodynia: UPDATe)
Award Date: 6/22/22
Funding Agency: National Institutes of Health
Grant Amount: $1,492,192
Miles Berger, MD, PhD
APOE4 dependent regulation of CSF Complement Pathway Activation in the development of Alzheimer's Disease
Award Date: 6/22/22
Funding Agency: National Institutes of Health
Grant Amount: $810,435
Miles Berger, MD, PhD
Neuro-inflammation in Postoperative Cognitive Dysfunction: CSF and fMRI Studies
Award Date: 6/14/22
Funding Agency: National Institutes of Health
Grant Amount: $214,794
Vijay Krishnamoorthy, MD, MPH, PhD
Mechanisms and Clinical Impact of Myocardial Injury Following Traumatic Brain Injury
Award Date: 5/27/2022
Funding Agency: National Institutes of Health
Grant Amount: $377,762
Richard E. Moon, MD, CM, MSc, FRCP, FACP, FCCP
Perfluoromethane to Reduce Decompression Sickness
Award Date: 5/19/2022
Funding Agency: Naval Sea Systems Command
Grant Amount: $398,428
Michael Devinney, MD, PhD
The Association of Blood-Brain Barrier Breakdown with Sleep Apnea and Postoperative Delirium
Award Date: 5/7/22
Funding Agency: National Institutes of Health
Grant Amount: $161,000
Andrea G. Nackley, PhD
A Novel Clinically-Relevant Mouse Model of Chronic Overlapping Pain Conditions for Screening Analgesics
Award Date: 4/20/22
Funding Agency: National Institutes of Health
Grant Amount: $1,106,152
Wei Yang, PhD, FAHA
The Unfolded Protein Response and Neuroprotection in Stroke
Award Date: 4/19/22
Funding Agency: National Institutes of Health
Grant Amount: $2,012,500
Jamie R. Privratsky, MD, PhD
The Role of the IL-1 Receptor in the AKI to CKD Transition
Award Date: 4/19/22
Funding Agency: National Institutes of Health
Grant Amount: $375,708
David S. Warner, MD
Integrated Training in Anesthesiology Research
Award Date: 3/29/22
Funding Agency: National Institutes of Health
Grant Amount: $1,714,260
Madan M. Kwatra, PhD
IL-13Ra1 Signaling in Atopic Dermatitis
Award Date: 2/23/22
Funding Agency: ASLAN Pharmaceuticals