Niccolò Terrando, BSc, DIC, PhD (Multi-PI)
Impact of Hypertension and Aging on Postoperative Delirium
Award Date: 5/20/2025
Funding Agency: National Institutes of Health/National Institute on Aging
Grant Amount: $3,465,825.00
Katherine T. Martucci, PhD
Neural Correlates and Behavioral Impact of Withdrawal-Induced Hyperalgesia Among People Who Smoke With and Without Chronic Pain
Award Date: 3/28/2025
Funding Agency: National Institutes of Health’s National Institute on Drug Abuse
Grant Amount: $3,488,576
Satya Achanta, DVM, PhD
IntraVascular Membrane Oxygenator Catheter
Award Date: 1/17/2025
Funding Agency: Department of Health and Human Services
Grant Amount: $199,962
Niccolò Terrando, BSc, DIC, PhD (Multi-PI)
IL-6 Trans-signaling Increases Vulnerability to Postoperative Cognitive Decline in Aging and Alzheimer's Disease
Award Date: 12/18/24
Funding Agency: National Institute on Aging | National Institutes of Health
Grant Amount: $349,190
Niccolò Terrando, BSc, DIC, PhD (Multi-PI)
IL-6 Trans-signaling Increases Vulnerability to Postoperative Cognitive Decline in Aging and Alzheimer's Disease
Award Date: 9/6/2024
Funding Agency: National Institute on Aging | National Institutes of Health
Grant Amount: $4,803,691
Niccolò Terrando, BSc, DIC, PhD
The Impacts of Postoperative Delirium on AD Progression
Award Date: 9/5/24
Funding Agency: Alzheimer's Association
Grant Amount: $199,969
Satya Achanta, PhD, DVM
Identification and Optimization of Medical Countermeasures for Phosgene Inhalation Injuries
Award Date: 8/21/2024
Funding Agency: National Institute of Environmental Health Sciences | National Institutes of Health
Grant Amount: $1,109,637
Sven-Eric Jordt, PhD
Impact of New Tobacco Product Design and Synthetic Additives on Use Initiation and Preference Behavior
Award Date: 8/13/2024
Funding Agency: National Institute on Drug Abuse | National Institutes of Health
Grant Amount: $2,395,528
Satya Achanta, DVM, PhD
Spinal Cord Stimulation for Treating Lower Back Pain in a Translational Swine Model
Award Date: 8/9/2024
Funding Agency: Presidio Medical, Inc.
Chengcheng Song, MD, PhD & Niccolò Terrando, BSc, DIC, PhD
The Impacts of Postoperative Delirium on Alzheimer’s Disease Progression
Award Date: 8/5/2024
Funding Agency: Alzheimer’s Association
Grant Amount: $199,969
Andrea G. Nackley, PhD
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments (Vestibulodynia: UPDATe)
Award Date: 6/7/2024
Funding Agency: Eunice Kennedy Shriver National Institute of Child Health & Human Development | National Institutes of Health
Grant Amount: $257,632
Satya Achanta, DVM, PhD
Discovery of Phosgene and Chlorine Gas Modes of Action and Therapeutic Targets Using Chemoproteomic Profiling Strategies
Award Date: 5/24/2024
Funding Agency: Pacific Northwest National Laboratory | National Institutes of Health
Grant Amount: $224,104
Ru-Rong Ji, PhD
Targeting Checkpoint Inhibitors for Pain Control
Award Date: 9/21/2023
Award Type: R01
Funding Agency: National Institutes of Health
Grant Amount: $2,569,851
Andrea G. Nackley, PhD
Development of Adrb3 Antagonists for the Treatment of Pain
Award Date: 9/8/2023
Award Type: R61
Funding Agency: National Institutes of Health
Grant Amount: $1,846,202
Andrea G. Nackley, PhD
MicroRNA 374 as an Epigenetic Regulator of Chronic Pain
Award Date: 7/17/2023
Funding Agency: National Institutes of Health
Grant Amount: $128,409
Andrea G. Nackley, PhD
Peripherally-Targeted Adrb3 Antagonists for the Treatment of Pain
Award Date: 4/1/2023
Funding Agency: University of North Carolina’s Eshelman Institute for Innovation
Grant Amount: $374,887
Niccolò Terrando, BSc, DIC, PhD
Microglia-Amyloid Interactions in Delirium Superimposed on Dementia
Award Date: 12/26/2022
Funding Agency: National Institutes of Health/National Institute on Aging
Grant Amount: $4,311,630
Shad Smith, PhD
Single-Cell Omics Approaches to Investigate TMD
Award Date: 10/21/2022
Funding Agency: NIH/National Institute of Dental and Craniofacial Research
Grant Amount: $402,487
Christopher R. Donnelly, DDS, PhD
Neural Architecture of the Murine and Human Temporomandibular Joint
Award Date: 10/13/22
Funding Agency: National Institutes of Health
Grant Amount: $5,734,530
Miriam M. Treggiari, MD, PhD, MPH
Randomized Trial of Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia - Prevent 2 Study
Award Date: 9/30/22
Funding Agency: National Institutes of Health
Grant Amount: $743,776
Thomas Van de Ven, MD, PhD
Single Nucleus Expression Profiling of Human Sciatic Nerve after Traumatic Amputation: Predicting Pain and Functional Outcomes
Award Date: 9/22/22
Funding Agency: Department of Defense
Grant Amount: $1,426,733
Katherine Martucci, PhD
Neurobiological Consequences of Long-Term Opioid Therapy in the Brain and Spinal Cord
Award Date: 9/20/2022
Award Type: R01
Funding Agency: National Institutes of Health
Grant Amount: $3,195,387
Christopher R. Donnelly, DDS, PhD, Shad Smith, PhD
Sexually Dimorphic Pain Signaling Mechanisms
Award Date: 9/14/22
Funding Agency: National Institutes of Health
Grant Amount: $2,132,329
Niccolò Terrando, BSc, DIC, PhD
Immunovascular Interactions in Postoperative Delirium Superimposed on Dementia (DSD)
Award Date: 9/14/22
Funding Agency: National Institutes of Health
Grant Amount: $2,244,681
Sven-Eric. Jordt, PhD
Nicotine Pouches: Chemical Composition, Toxicity and Behavioral Effects of a New Tobacco Product Category
Award Date: 9/2/22
Funding Agency: National Institutes of Health
Grant Amount: $416,512
Satyanarayana Achanta, DVM, PhD, Sven-Eric. Jordt, PhD
Pulmonary Cell Fate and Lung Repair in Rodent and Porcine Models of Chlorine and Phosgene Inhalation Injuries
Award Date: 9/2/2022
Award Type: R01
Funding Agency: NIH/National Institute of Environmental Health Sciences
Grant Amount: $1,430,370
Christopher R. Donnelly, DDS, PhD
Neuro-Immune Modulation of Pain in Health and Disease
Award Date: 9/2/2022
Award Type: R01
Funding Agency: National Institutes of Health
Grant Amount: $3,311,196
Christopher R. Donnelly, DDS, PhD
Identifying Non-Opioid Strategies to Manage Oral Cancer Pain
Award Date: 9/1/2022
Funding Agency: University of Michigan
Andrea G. Nackley, PhD
Defining the Role of Peripheral Adrb3 in Chronic Pain and Inflammation
Award Date: 7/28/22
Funding Agency: National Institutes of Health
Grant Amount: $1,039,036
Ru-Rong Ji, PhD
Pain Management in Critical Combat Casualty Environments using Resorbable Poly(ester urea) Films for Sustained Delivery of Meloxicam and Bupivacaine
Award Date: 7/28/22
Funding Agency: Department of Defense
Grant Amount: $1,517,530
Ru-Rong Ji, PhD
Developing Non-Opiate GPCR Signaling Biased Agents for Pain Management
Award Date: 7/28/22
Funding Agency: Department of Defense
Grant Amount: $1,608,140
Satyanarayana Achanta, DVM, PhD
Inhibition of Soluble Epoxide Hydrolase Protects Against Phosgene-Induced Lung Injuries
Award Date: 7/27/22
Funding Agency: National Institutes of Health
Grant Amount: $201,250
Andrea G. Nackley, PhD
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments (Vestibulodynia: UPDATe)
Award Date: 6/22/22
Funding Agency: National Institutes of Health
Grant Amount: $1,492,192
Andrea G. Nackley, PhD
A Novel Clinically-Relevant Mouse Model of Chronic Overlapping Pain Conditions for Screening Analgesics
Award Date: 4/20/22
Funding Agency: National Institutes of Health
Grant Amount: $1,106,152
Ru-Rong Ji, PhD
Prevention of Pain Chronification and Neuroinflammation After Traumatic Brain Injury by Neuroprotectin D1 and GPR37 Signaling
Award Date: 8/27/2021
Funding Agency: Department of Defense
Grant Amount: $1,444,257
Ru-Rong Ji, PhD
Monoclonal Antibody-Based Therapeutics for Targeting MMPs and Diabetic Neuropathy
Award Date: 8/27/2021
Funding Agency: Department of Defense
Grant Amount: $1,601,314
Satya Achanta, DVM, PhD, DABT
Inhibition of Soluble Epoxide Hydrolase Protects Against Phosgene-Induced Lung Injuries
Award Date: 8/16/2021
Award Type: R21
Funding Agency: National Institutes of Health
Grant Amount: $442,750
Niccolò Terrando, BSc, DIC, PhD
Immunoprofiling Postoperative Delirium During Aging and Neurodegeneration
Award Date: 7/26/2021
Award Type: R21
Funding Agency: National Institutes of Health’s National Institute on Aging
Grant Amount: $239,843
Andrea G. Nackley, PhD
Defining the Role of Peripheral Adrb3 in Chronic Pain and Inflammation
Award Date: 7/19/2021
Funding Agency: National Institutes of Health
Grant Amount: $534,634
Andrea G. Nackley, PhD
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments (Vestibulodynia: UPDATe)
Award Date: 7/9/2021
Funding Agency: National Institutes of Health
Grant Amount: $2,260,197
Niccolò Terrando, BSc, DIC, PhD
Neurovascular Dysfunction in Delirium Superimposed on Dementia
Award Date: 5/18/2021
Funding Agency: National Institutes of Health
Grant Amount: $526,781
Satya Achanta, DVM, PhD, DABT
Specialized Pro-Resolving Mediators as Potential Medical Countermeasures in a Pig Model of Chlorine Gas-Induced Acute Lung Injury
Award Date: 5/6/2021
Funding Agency: National Institutes of Health
Grant Amount: $241,500
Thomas E. Buchheit, MD
Neuronal and Glial Interactions of Neuropathic Pain
Award Date: 4/29/2021
Funding Agency: National Institutes of Health
Grant Amount: $488,534
William Maixner, DDS, PhD
Role of Preoperative Baroreflex Sensitivity on Postoperative and Persistent Pain after Thoracic Surgery
Award Date: 2/3/2021
Funding Agency: National Institutes of Health
Grant Amount: $201,250
Sven-Eric Jordt, PhD
Project 1: Effects of Flavors on Nicotine Choice and Central Reward Me
Award Date: 1/28/2021
Funding Agency: Yale University
Grant Amount: $276,375
Evan D. Kharasch, MD, PhD
Optimizing Outpatient Anesthesia: Improving Analgesia and Reducing Opioid Misadventure
Award Date: 12/21/2020
Funding Agency: National Institutes of Health
Grant Amount: $505,170
Niccolò Terrando, BSc, DIC, PhD
Test the Efficacy of Exalys EP4 Antagonist to Prevent Neuroinflamation and Delirium in a Preclinical Model
Award Date: 12/16/2020
Funding Agency: Exalys Therapeutics, Inc
Grant Amount: $200,479
Sven-Eric Jordt, PhD
Biomarkers of Lung Injury in Methyl Isocyanate Exposed Rodents and Pigs
Award Date: 11/24/2020
Funding Agency: University of Colorado – Denver
Grant Amount: $105,838
Satya Achanta, DVM, PhD
Intraganglionic Analgesic Adeno-Associated Virus (AAV) Gene Vector Optimization in Large Animals
Award Date: 11/4/2020
Funding Agency: Interventional AnalgesiX, Inc.
Grant Amount: $147,100
Niccolò Terrando, BSc, DIC, PhD
Delirium Superimposed on Dementia Intersects with COVID-19
Award Date: 9/2/2020
Award Type: R01
Funding Agency: National Institutes of Health
Grant Amount: $322,620
Sven-Eric Jordt, PhD
Advanced TRPA1 Inhibitor for the Treatment of Chlorine Inhalation Injury
Award Date: 9/2/2020
Funding Agency: National Institutes of Health
Grant Amount: $769,835
Sven-Eric Jordt, PhD
Anesthetic and Synthetic Cooling Flavors in E-cigarettes: Chemistry and Respiratory Effects Modulating Nicotine Intake
Award Date: 7/30/2020
Funding Agency: National Institutes of Health
Grant Amount: $769,835
Katherine Martucci, PhD
The Impact of Opioids on Chronic Pain: Clinical Research and Career Training in Spinal Cord fMRI and Brain Reward Systems
Award Date: 7/20/2020
Funding Agency: National Institutes of Health
Grant Amount: $248,784
William Maixner, DDS, PhD
Neuronal and Glial Interactions of Neuropathic Pain
Award Date: 7/15/2020
Funding Agency: National Institutes of Health
Grant Amount: $488,534
Andrea G. Nackley, PhD
Defining the Role of Peripheral Adrb3 in Chronic Pain and Inflammation
Award Date: 7/15/2020
Funding Agency: National Institutes of Health
Grant Amount: $524,671
William Maixner, DDS, PhD
Role of Preoperative Baroreflex Sensitivity on Postoperative and Persistent Pain after Thoracic Surgery
Award Date: 6/18/2020
Funding Agency: National Institutes of Health
Grant Amount: $201,250
Andrea G. Nackley, PhD
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments (Vestibulodynia: UPDATe)
Award Date: 6/17/2020
Funding Agency: National Institutes of Health
Grant Amount: $768,005
David S. Warner, MD
Integrated Training in Anesthesiology Research
Award Date: 6/9/2020
Funding Agency: National Institutes of Health
Grant Amount: $314,587
Satya Achanta, DVM, PhD
Specialized Pro-Resolving Mediators as Potential Medical Countermeasures in a Pig Model of Chlorine Gas-Induced Acute Lung Injury
Award Date: 5/29/2020
Funding Agency: National Institutes of Health
Grant Amount: $442,750
Niccolò Terrando, BSc, DIC, PhD
Resolution of Postoperative Pain by Complementary Approaches
Award Date: 4/22/2020
Funding Agency: National Institutes of Health
Grant Amount: $1,505,715
Andrea G. Nackley, PhD
Resolving Functional Pain by Complementary Approaches
Award Date: 4/22/2020
Funding Agency: National Institutes of Health
Grant Amount: $1,394,879
Sven-Eric Jordt, PhD
Molecular Core
Award Date: 4/22/2020
Funding Agency: National Institutes of Health
Grant Amount: $1,553,621
William Maixner, DDS, PhD
Administrative Core
Award Date: 4/22/2020
Funding Agency: National Institutes of Health
Grant Amount: $1,215,178
Niccolò Terrando, BSc, DIC, PhD
Neurovascular Dysfunction in Delirium Superimposed on Dementia
Award Date: 4/16/2020
Funding Agency: National Institutes of Health
Grant Amount: $561,845
Niccolò Terrando, BSc, DIC, PhD
Targeting Microbially-Derived Juvenile Protective Factors to Resolve Neuroinflammation and Delirium
Award Date: 3/10/2020
Funding Agency: National Institutes of Health
Grant Amount: $161,000
Evan D. Kharasch, MD, PhD
Optimizing Outpatient Anesthesia: Improving Analgesia and Reducing Opioid Misadventure
Award Date: 1/24/2020
Funding Agency: National Institutes of Health
Grant Amount: $559,927
Andrea G. Nackley, PhD
Defining the Role of Peripheral Adrb3 in Chronic Pain and Inflammation
Award Date: 9/5/2019
Award Type: R01
Funding Agency: NIH and the National Institute of Neurological Disorders and Stroke (NINDS)
Grant Amount: $2,623,436
David S. Warner, MD
Pharmacologic Suppression of Reperfusion Injury Following Endovascular Thrombectomy In Stroke
Award Date: 9/2/2019
Funding Agency: NIH and the National Institute of Neurological Disorders and Stroke (NINDS)
Grant Amount: $475,175
Sven-Eric Jordt, PhD and Satya Achanta, DVM, PhD
Advanced TRPA1 Inhibitor for the Treatment of Chlorine Inhalation Injury
Award Date: 8/26/2019
Award Type: U01
Funding Agency: NIH and the National Institute of Environmental Health Services (NIEHS)
Grant Amount: $2,305,444
Dr. Maixner Named IASP Honorary Member
Congratulations to William Maixner, DDS, PhD, on being named an Honorary Member of the International Association for the Study of Pain (IASP). Honorary membership is the highest honor IASP can bestow on a member and recognizes outstanding contributions to the field. Dr. Maixner will be honored during the 2020 IASP General Assembly at the 18th World Congress on Pain in Amsterdam on August 8th.
Niccolò Terrando, BSc (hons), DIC, PhD
Bioelectronic Regulation of CNS Lymphatic Drainage in Delirium and AD
Award Date: 8/23/2019
Funding Agency: Alzheimer’s Association
Grant Amount: $150,000
Ru-Rong Ji, PhD
Resolving Neuropathic Pain With High Frequency SCS Via Modulation of Glial Signaling and Neuroinflammation in Small and Large Animals
Award Date: 7/26/2019
Funding Agency: Boston Scientific Corporation
Grant Amount: $320,889
Niccolò Terrando, BSc (hons), DIC, PhD and Paul E. Wischmeyer, MD, EDIC
Targeting Microbially-Derived Juvenile Protective Factors to Resolve Neuroinflammation and Delirium
Award Date: 7/13/2019
Award Type: R03
Funding Agency: National Institutes of Health
Grant Amount: $322,000
Andrea Nackley, PhD
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments (Vestibulodynia: UPDATe)
Award Date: 9/11/2018
Award Type: NIH R01
Funding Agency: National Institutes of Health’s National Institute of Child Health and Human Development
Grant Amount: $3,846,094
Katherine Martucci, PhD
The Impact of Opioids on Chronic Pain: Clinical Research and Career Training in Spinal Cord fMRI and Brain Reward Systems
Award Date: 8/14/2018
Award Type: NIH R00
Funding Agency: National Institutes of Health’s (NIH) National Institute on Drug Abuse (NIDA)
Grant Amount: $746,654
Sven-Eric Jordt, PhD
Anesthetic and Synthetic Cooling Flavors in E-cigarettes: Chemistry and Respiratory Effects Modulating Nicotine Intake
Award Date: 7/19/2018
Award Type: NIH R01
Funding Agency: National institutes of Health, National Institute of Environmental Health Sciences (NIEHS)
Grant Amount: $1,456,395
Niccolò Terrando, BSc, DIC, PhD
Bioelectronic Rescue of Cognitive Impairment After Surgery
Award Date: 6/19/2018
Award Type: NIH R21
Funding Agency: National institute on Aging (NIA)
Grant Amount: $436,027
Niccolò Terrando, BSc, DIC, PhD
Omegaven and Postoperative Cognitive Dysfunction
Award Date: 4/18/2018
Funding Agency: Fresenius Kabi Deutschland GmbH
Grant Amount: $122,000
Andrea Nackley, PhD
Defining the Role of Adipocyte Adrb3 in Chronic Pain
Award Date: 1/9/2018
Funding Agency: National Institute of Neurological Disorders and Stroke (NINDS)
Grant Amount: $160,000
Xin Zhang, MD, PhD
Activation of Peripheral β2 and β3ARs Leads to Increased Nociceptor Activity
Award: Best of Abstracts
Award Date: 2/15/2018
Agency: Genetics and Pain Shared Interest Group of the American Pain Society
Niccolò Terrando, BSc, DIC, PhD
Neurovascular Dysfunction in Delirium Superimposed on Dementia
Award Date: 9/15/2017
Funding Agency: National Institutes of Health/National Institute on Aging – RO1
Grant Amount: $2,815,756
William Maixner, DDS, PhD
Chronic Overlapping Pain Conditions
Award Date: 3/20/2017
Funding Agency: University of North Carolina – Chapel Hill
Grant Amount: $158,998
Thomas E. Buchheit, MD
Germline Epigenetic Effects of Opioids (GEEO)
Award Date: 3/16/2017
Funding Agency: Research Triangle Institute International
Grant Amount: $79,999
Sven-Eric Jordt, PhD
Biomarkers of Lung Injury in Methyl Isocyanate Exposed Rodents and Pigs
Award Date: 2/10/2017
Funding Agency: University of Colorado – Denver
Grant Amount: $577,458
Andrea G. Nackley, PhD
Proteins, MicroRNAs and Genes Associated with TMD and Overlapping Conditions
Award Date: 9/1/2016
Funding Agency: National Institute of Dental and Craniofacial Research (NIH)
Grant Amount: $500,000
Niccolò Terrando, BSc, DIC, PhD
Role of TLR4 in Surgery-Induced Cognitive Decline
Award Date: 8/10/2016
Funding Agency: Takeda Pharmaceutical Company Limited
Grant Amount: $108,888
William Maixner, DDS, PhD
CTPM Director Appointed to European Pain School Board
Date: 8/1/2016
Niccolò Terrando, BSc, DIC, PhD
Bioelectronic Medicine and Cholinergic Regulation of Postoperative Cognitive Dysfunction
Award Date: 7/1/2016
Funding Agency: Duke Institute for Brain Sciences (DIBS)
Grant Amount: $75,000
Sven-Eric Jordt, PhD
Mechanisms of Itch in Poison Ivy-Induced Allergic Contact Dermatitis
Award Date: 6/24/2016
Funding Agency: National Institute of Arthritis and Musculoskeletal and Skin Diseases (R21)
Grant Amount: $384,780
Niccolò Terrando, BSc, DIC, PhD
Neuroprotective Effects of URMC-099 in Postoperative Cognitive Dysfunction
Award Date: 4/19/2016
Funding Agency: University of Rochester Medical Center
Grant Amount: $3,000
William Maixner, DDS, PhD
Genetic and Psychosocial Influences on Transition to Chronic TMD and Related Pain (OPPERA-2)
Award Date: 4/8/2016
Funding Agency: University of North Carolina – Chapel Hill/NIH
Grant Amount: $134,043